Evidence map›Paper›PMID 35475469›Full record

ArticleBioengineered2022

Long non-coding RNA MIR4435-2HG/microRNA-125a-5p axis is involved in myocardial ischemic injuries.

Xiuling Wang, Lina Ren, Shuai Chen, Yanli Tao, Dandan Zhao, Chunwei Wu

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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  11. Noncoding RNAs as Key Regulators for Cardiac Development and Cardiovascular Diseases.Journal of cardiovascular development and disease · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xiuling WangDepartment of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang110001, Liaoning Province, China.
Lina RenDepartment of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang110001, Liaoning Province, China.
Shuai ChenDepartment of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang110001, Liaoning Province, China.
Yanli TaoDepartment of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang110001, Liaoning Province, China.
Dandan ZhaoDepartment of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang110001, Liaoning Province, China.
Chunwei WuDepartment of Cardiology, The First Affiliated Hospital of China Medical University, Shenyang110001, Liaoning Province, China.ORCID 0000-0002-6755-7554
First Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate whether and how long non-coding RNA (lncRNA) MIR4435-2 host gene (MIR4435-2HG) involved in acute myocardial ischemia/reperfusion (I/R). Blood samples were collected from acute myocardial infarction (AMI) patients to detect MIR4435-2HG expression.

Indexed as

MicroRNAsRNA, Long NoncodingAnimalsApoptosisHumansHydrogen PeroxideMiceMyocytes, CardiacHydrogen PeroxideMicroRNAsMIR4435-2HG long non-coding RNA, humanRNA, Long NoncodingapoptosisMImiR-125a-5pMIR4435-2HGMTFP1

Identifiers

PMID35475469
PMCPMC9208505
OpenAlexW4224998618

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.