Trial reportJournal of athletic training2023
Exercise-Induced Changes in Femoral Cartilage Thickness in Patients With Patellofemoral Pain.
Trial report in Journal of athletic training, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Comparison of anti-gravity treadmill training and traditional treadmill training in patients with moderate to severe knee osteoarthritis: A randomized controlled trial.Irish journal of medical science · 2025Trial
- Article
- Design and Performance Study of a Gradient Honeycomb Vibration-Damping Structure for the Knee Joint.Biomimetics (Basel, Switzerland) · 2026Article
- Individuals with patellofemoral pain have impaired self-reported and performance-based function: Systematic review with meta-analysis and meta-regression.Journal of athletic training · 2024Article
- Morphologic Response in Femoral Cartilage During and After 40-Minute Treadmill Running.Journal of athletic training · 2024Article
- The Role of the Ultrasonographic Knee Assessment in the Diagnosis of Patellofemoral Pain Syndrome : Ultrasonography and Patellofemoral Pain Syndrome.Galen medical journal · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextRehabilitative exercises alleviate pain in patients with patellofemoral pain (PFP); however, no researchers have analyzed the cartilage response after a bout of those athletic activities in patients with PFP.
objectiveTo determine if a single session of rehabilitative exercises alters femoral cartilage morphology.
designCrossover study.
settingResearch laboratory. PATIENTS OR OTHER
participantsTwelve participants with PFP (age = 21.0 ± 2.0 years, height = 1.72 ± 0.1 m, mass = 68.7 ± 12.6 kg) and 12 matched healthy participants (age = 21.3 ± 2.8 years, height = 1.71 ± 0.1 m, mass = 65.9 ± 12.2 kg) were enrolled. INTERVENTION(S): Participants completed treadmill running, lower extremity strengthening exercises, and plyometric exercises for 30 minutes each. MAIN OUTCOME MEASURE(S): Patient-reported outcomes on the visual analog scale, Anterior Knee Pain Scale (AKPS), Knee injury and Osteoarthritis Outcome Score (KOOS), and Knee Injury and Osteoarthritis Outcome Score for Patellofemoral Pain and Osteoarthritis were collected. Femoral cartilage ultrasonographic images were obtained at 140° of knee flexion. Ultrasound images were segmented into medial and lateral images using the intercondylar notch. Medial and lateral cartilage cross-sectional area (mm2) and echo intensity (EI), defined as the average grayscale from 0 to 255, were analyzed by ImageJ software. The difference between loading conditions was calculated using repeated-measures analysis of variance. The Spearman correlation was calculated to find the association between the cartilage percentage change (Δ%) and patient-reported outcomes.
resultsPain increased in the PFP group after all loading conditions (P values < .007). No differences were found in cartilage cross-sectional area or EI alteration between or within groups (P values > .06). The KOOS was negatively associated with the Δ% of the lateral femoral cartilage EI after plyometric loading (ρ = -0.87, P = .001), and the AKPS score was positively correlated with the Δ% of lateral femoral cartilage EI (ρ = 0.57, P = .05).
conclusionsUltrasound imaging did not identify cartilaginous deformation after all loading conditions. However, because lateral cartilaginous EI changes were associated with the AKPS and KOOS score, those questionnaires may be useful for monitoring changes in femoral cartilage health.
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