Evidence map›Paper›PMID 35476172›Full record

ArticleMolecular biology reports2022

Comparative liver transcriptome analysis of duck reveals potential genes associated with egg production.

Koodali Nimisha, Krishnamoorthy Srikanth, Dinesh Velayutham, Dharam Nandan, Shanmugam Sankaralingam, Muniyandi Nagarajan

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Article in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Koodali NimishaDepartment of Genomic Science, School of Biological Sciences, Central University of Kerala, 671316, Kasaragod, Kerala, India.ORCID http://orcid.org/0000-0003-4502-7613
Krishnamoorthy SrikanthDepartment of Animal Science, College of Agriculture and Life Sciences, Cornell University, 14853, Ithaca, NY, United States.ORCID https://orcid.org/0000-0002-5205-193X
Dinesh VelayuthamAgriGenome Labs Pvt. Ltd, 682042, Kochi, Kerala, India.ORCID https://orcid.org/0000-0002-9425-7266
Dharam NandanAgriGenome Labs Pvt. Ltd, 682042, Kochi, Kerala, India.
Shanmugam SankaralingamDepartment of Poultry Science, College of Veterinary and Animal Sciences, 680 651, Mannuthy, Thrissur, Kerala, India.
Muniyandi NagarajanDepartment of Genomic Science, School of Biological Sciences, Central University of Kerala, 671316, Kasaragod, Kerala, India. nagarajan@cukerala.ac.in.ORCID https://orcid.org/0000-0001-8328-9767
Central University of Kerala · INSciGenom Labs (India) · INCornell University · USKerala Veterinary and Animal Sciences University · IN

Funding

Department of Biotechnology BT/PR14584/AAQ/1/647/2015Science and Engineering Research Board EEQ/2016/000390
6 · The paper itself

Abstract

backgroundMolecular studies on egg production in ducks were mostly focused on brain and ovaries as they are directly involved in egg production. Liver plays a vital role in cellular lipid metabolism. It also plays a decisive role in reproductive organ development, including yolk generation in laying ducks at sexual maturity. However, the precise molecular mechanism involved in the liver-blood-ovary axis in ducks remains elusive. METHODS AND

resultsIn this study, we analysed the liver transcriptome of laying (LA), immature (IM) and broody (BR) ducks using RNA sequencing to understand the role of genes expressed in the liver. The comparative transcriptome analysis revealed 82 DEGs between LA and IM ducks, 47 DEGs between LA and BR ducks and 51 DEGs between IM and BR ducks. GO analysis of DEGs, showed that DEGs were mainly involved in cellular anatomical entity, intracellular, metabolic process, and binding. Furthermore, pathway analysis indicated the important role of Wnt signaling pathway in egg formation and embryo development. Our study showed several candidate genes including vitellogenin-1, vitellogenin-2, riboflavin binding protein, G protein subunit gamma 4, and fatty acid binding protein 3 that are potentially related to egg production in ducks.

conclusionsThe study provides valuable information on the genes responsible for egg production and thus, pave the way for further investigation on the molecular mechanisms of egg production in duck.

Indexed as

DucksTranscriptomeAnimalsFemaleGene Expression ProfilingLiverVitellogeninsVitellogeninsDuckEggLayingLiverTranscriptome

Identifiers

PMID35476172
OpenAlexW4224984578

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.