Evidence map›Paper›PMID 35477306›Full record

ArticlemSystems2022

Gut Microbiome Alterations Associated with Diabetes in Mexican Americans in South Texas.

Suet-Ying Kwan, Caroline M Sabotta, Aron Joon, Peng Wei, Lauren E Petty, Jennifer E Below, Xiaogang Wu, Jianhua Zhang, Robert R Jenq, Ernest T Hawk and 3 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
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  20. Diabetes and gut microbiome.Frontiers in microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Suet-Ying KwanDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.
Caroline M SabottaDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.
Aron JoonDepartment of Biostatistics, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.
Peng WeiDepartment of Biostatistics, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.
Lauren E PettyVanderbilt Genetics Institute and Department of Genetic Medicine, Vanderbilt University Medical Centergrid.412807.8, Nashville, Tennessee, USA.
Jennifer E BelowVanderbilt Genetics Institute and Department of Genetic Medicine, Vanderbilt University Medical Centergrid.412807.8, Nashville, Tennessee, USA.
Xiaogang WuDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.
Jianhua ZhangDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.
Robert R JenqDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.
Ernest T HawkDepartment of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.
Joseph B McCormickSchool of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, Texas, USA.
Susan P Fisher-HochSchool of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, Texas, USA.
Laura BerettaDepartment of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Centergrid.240145.6, Houston, Texas, USA.ORCID 0000-0002-2054-684X
The University of Texas MD Anderson Cancer Center · USVanderbilt University Medical Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
Center for Clinical and Translational Sciences (CCTS)UL1TR000371 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2012 to 2016
$13.4M
The University of Texas MD Anderson Cancer Center SPORE in Hepatocellular CarcinomaP50CA217674 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YAO, JAMES C · 2019 to 2023
$11.3M
NCATS NIH HHS UL1 TR000371NCATS NIH HHS UL1 TR003167NCI NIH HHS P30 CA016672NCI NIH HHS P50 CA217674
6 · The paper itself

Abstract

Mexican Americans have a high prevalence of diabetes and burden of diabetes-related complications, highlighting the need for novel preventive strategies and noninvasive predictors of diabetes risk tailored to this population. Changes in the gut microbiome have the potential to predict diabetes. Here, we aimed to identify alterations in the gut microbiome associated with diabetes in the high-risk population of Mexican Americans in South Texas. Stool samples were collected from 216 subjects from the population-based Cameron County Hispanic Cohort. Among them, 75 had type 2 diabetes. Taxonomic and functional profiling of the stool samples were assessed by 16S and shotgun metagenomic sequencing, and the influence of genetic factors was explored. The gut microbiome of subjects with diabetes was enriched with proinflammatory Proteobacteria members (Enterobacteriaceae, Escherichia

Indexed as

Diabetes Mellitus, Type 2Gastrointestinal MicrobiomeButyratesEnterobacteriaceaeHumansMexican AmericansProspective StudiesTexasButyratesdiabetesgut microbiomehealth disparitymetagenomeMexican American population

Identifiers

PMID35477306
PMCPMC9238400
OpenAlexW4225014989

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.