Evidence map›Paper›PMID 35496277›Full record

ArticleFrontiers in pharmacology2022

Population Pharmacokinetics of Intravenous Acyclovir in Oncologic Pediatric Patients.

Natalia Maximova, Daniela Nisticò, Giacomo Luci, Roberto Simeone, Elisa Piscianz, Ludovica Segat, Egidio Barbi, Antonello Di Paolo

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05198570 (Pharmacokinetics of Intravenous Acyclovir in Children Undergoing Hematopoietic Stem Cell Transplantation or High-intensity Antineoplastic Chemotherapy), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05198570 recruitingnot on this map

Pharmacokinetics of Intravenous Acyclovir in Children Undergoing Hematopoietic Stem Cell Transplantation or High-intensity Antineoplastic Chemotherapy

TypeobservationalSponsorUniversity of PisaRan2021 to 2026Enrolled200ConditionsHerpesviridae Infections, Herpes Simplex 1, Varicella Zoster Virus Infection, Transplantation InfectionArmsPharmacokinetic analysis
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Effects of plateau hypoxia on population pharmacokinetics and pharmacodynamics of metformin in patients with Type 2 diabetes.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Natalia MaximovaDepartment of Pediatrics, Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.
Daniela NisticòDepartment of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.
Giacomo LuciDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Roberto SimeoneTransfusion Medicine Department, Azienda Sanitaria Universitaria "Giuliano Isontina", Trieste, Italy.
Elisa PiscianzLaboratory for Hygiene and Public Health, University Hospital of Trieste, Trieste, Italy.
Ludovica SegatLaboratory for Hygiene and Public Health, University Hospital of Trieste, Trieste, Italy.
Egidio BarbiDepartment of Pediatrics, Institute for Maternal and Child Health-IRCCS Burlo Garofolo, Trieste, Italy.
Antonello Di PaoloDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
University of Trieste · ITUniversity of Pisa · ITAzienda Sanitaria Universitaria Integrata di Trieste · ITIRCCS Materno Infantile Burlo Garofolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acyclovirchildrenhematopoietic stem cell transplantationnon-linear mixed effect modelingpediatric patientspharmacokineticsprolonged infusionprolonged infusion acyclovir

Identifiers

PMID35496277
PMCPMC9050193
OpenAlexW4223962536

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.