Evidence map›Paper›PMID 35498006›Full record

ReviewFrontiers in cardiovascular medicine2022

Imaging Assessment of Endothelial Function: An Index of Cardiovascular Health.

Anum S Minhas, Erin Goerlich, Mary C Corretti, Armin Arbab-Zadeh, Sebastian Kelle, Thorsten Leucker, Amir Lerman, Allison G Hays

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Metabolic and redox pathway dysregulation in HIV-associated coronary endothelial dysfunction.American journal of physiology. Heart and circulatory physiology · 2026
    Observational
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Coronary artery endothelial function and aging in people with HIV and HIV-negative individuals.American journal of physiology. Heart and circulatory physiology · 2023
    Article
  18. Observational
  19. Coronary atherosclerosis and chemotherapy: From bench to bedside.Frontiers in cardiovascular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Anum S MinhasDivision of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Erin GoerlichDivision of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Mary C CorrettiDivision of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Armin Arbab-ZadehDivision of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Sebastian KelleDepartment of Internal Medicine and Cardiology, German Heart Center Berlin, Berlin, Germany.
Thorsten LeuckerDivision of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Amir LermanDivision of Ischemic Heart Disease and Critical Care, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States.
Allison G HaysDivision of Cardiology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Johns Hopkins Medicine · USJohns Hopkins University · USDeutsches Herzzentrum der Charité · DEMayo Clinic · US

Funding

Emerging factors in the pathophysiology of endothelial dysfunction in HIV+ womenR01HL147660 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI HAYS, ALLISON G · 2019 to 2023
$1.4M
NHLBI NIH HHS R01 HL147660
6 · The paper itself

Abstract

Endothelial dysfunction is a key early mechanism in a variety of cardiovascular diseases and can be observed in larger conduit arteries as well as smaller resistance vessels (microvascular dysfunction). The presence of endothelial dysfunction is a strong prognosticator for cardiovascular events and mortality, and assessment of endothelial function can aid in selecting therapies and testing their response. While the gold standard method of measuring coronary endothelial function remains invasive angiography, several non-invasive imaging techniques have emerged for investigating both coronary and peripheral endothelial function. In this review, we will explore and summarize the current invasive and non-invasive modalities available for endothelial function assessment for clinical and research use, and discuss the strengths, limitations and future applications of each technique.

Indexed as

CADCMRcoronary MRIendothelial functionvascular disease

Identifiers

PMID35498006
PMCPMC9051238
OpenAlexW4223982304

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.