Evidence map›Paper›PMID 35502372›Full record

ArticleQuantitative imaging in medicine and surgery2022

Associations between carotid atherosclerotic plaque characteristics determined by magnetic resonance imaging and improvement of cognition in patients undergoing carotid endarterectomy.

Ran Huo, Ying Liu, Huimin Xu, Jin Li, Ruijing Xin, Zhangli Xing, Shasha Deng, Tao Wang, Huishu Yuan, Xihai Zhao

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  6. CA IX-targeted AgJournal of pharmaceutical analysis · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Ran Huo *Department of Radiology, Peking University Third Hospital, Beijing, China.
Ying Liu *Department of Radiology, Peking University Third Hospital, Beijing, China.
Huimin XuDepartment of Radiology, Peking University Third Hospital, Beijing, China.
Jin LiDepartment of Radiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Ruijing XinDepartment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Zhangli XingDepartment of Radiology, Fujian Medical University Union Hospital, Fuzhou, China.
Shasha DengSchool of Medical Imaging, Changsha Medical University, Changsha, China.
Tao Wang *Department of Neurosurgery, Peking University Third Hospital, Beijing, China.
Huishu Yuan *Department of Radiology, Peking University Third Hospital, Beijing, China.
Xihai ZhaoCenter for Biomedical Imaging Research, Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Peking University · CNPeking University Third Hospital · CNBeijing Chao-Yang Hospital · CNChangsha Medical University · CNNanjing Drum Tower Hospital · CNTsinghua University · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To determine the predictive value of carotid plaque characteristics for the improvement of cognition in patients with moderate-to-severe carotid stenosis after carotid endarterectomy (CEA), using vessel wall magnetic resonance imaging (MRI). Methods: This was a prospective cohort study. Patients with unilateral, moderate-to-severe carotid stenosis referred to the Peking University Third Hospital for CEA were prospectively recruited and underwent carotid vessel wall MRI within 1 week before CEA. We performed Montreal Cognitive Assessment (MoCA) within 1 week before and 3-4 days after CEA. The morphological and compositional characteristics of carotid plaques on MRI were evaluated. Improvement of cognition was defined as >10% increase of the total MoCA score after CEA compared with baseline. Carotid plaque characteristics were compared between patients with and without cognitive improvement. Results: In total, 105 patients (91 males; mean age, 65.5±8.4 years) were included. The volume {48.0 [interquartile range (IQR), 21.0 to 91.6] Conclusions: More than half of the participants with unilateral, moderate-to-severe carotid atherosclerotic stenosis had cognitive improvement. The size of calcification might be an effective indicator of cognitive improvement after CEA.

Indexed as

atherosclerosisCarotid arterycarotid endarterectomy (CEA)cognitive functionvessel wall magnetic resonance imaging (vessel wall MRI)

Identifiers

PMID35502372
PMCPMC9014142
OpenAlexW4225398128

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.