Evidence map›Paper›PMID 35510897›Full record

SynthesisThe European journal of general practice2022

Family history tools for primary care: A systematic review.

Špela Miroševič, Zalika Klemenc-Ketiš, Borut Peterlin

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in The European journal of general practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. US Immigrants and their Knowledge of their Family History of Cancer: A Population-Based Study.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Špela MiroševičDepartment of Family Medicine, Medical Faculty Ljubljana, Ljubljana, Slovenia.ORCID 0000-0001-5004-0607
Zalika Klemenc-KetišDepartment of Family Medicine, Medical Faculty Ljubljana, Ljubljana, Slovenia.
Borut PeterlinClinical Institute for Medical Genetics, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Ljubljana University Medical Centre · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany medical family history (FH) tools are available for various settings. Although FH tools can be a powerful health screening tool in primary care (PC), they are currently underused.

objectivesThis review explores the FH tools currently available for PC and evaluates their clinical performance.

methodsFive databases were systematically searched until May 2021. Identified tools were evaluated on the following criteria: time-to-complete, integration with electronic health record (EMR) systems, patient administration, risk-assessment ability, evidence-based management recommendations, analytical and clinical validity and clinical utility.

resultsWe identified 26 PC FH tools. Analytical and clinical validity was poorly reported and agreement between FH and gold standard was commonly inadequately reported and assessed. Sensitivity was acceptable; specificity was found in half of the reviewed tools to be poor. Most reviewed tools showed a capacity to successfully identify individuals with increased risk of disease (6.2-84.6% of high and/or moderate or increased risk individuals).

conclusionDespite the potential of FH tools to improve risk stratification of patients in PC, clinical performance of current tools remains limited as well as their integration in EMR systems. Twenty-one FH tools are designed to be self-administered by patients.

Indexed as

Electronic Health RecordsPrimary Health CareHumansMedical History TakingRisk Assessmentgeneralgeneral practice/family medicineGeneticsincl. family historymeta-analysessystematic reviews

Identifiers

PMID35510897
PMCPMC9090347
OpenAlexW4229042141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.