Evidence map›Paper›PMID 35514973›Full record

ArticleFrontiers in immunology2022

Canonical NF-κB p65, but Not p105, Contributes to IL-1β-Induced IL-8 Expression in Cardiac Fibroblasts.

Masashi Mizuno, Rei Nakano, Saki Nose, Moeka Matsumura, Yasuyuki Nii, Kentaro Kurogochi, Hiroshi Sugiya, Masami Uechi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Masashi MizunoJapan Animal Specialty Medical Institute, Tsuzuki, Yokohama, Japan.
Rei NakanoJapan Animal Specialty Medical Institute, Tsuzuki, Yokohama, Japan.
Saki NoseJapan Animal Specialty Medical Institute, Tsuzuki, Yokohama, Japan.
Moeka MatsumuraJapan Animal Specialty Medical Institute, Tsuzuki, Yokohama, Japan.
Yasuyuki NiiJapan Animal Specialty Medical Institute, Tsuzuki, Yokohama, Japan.
Kentaro KurogochiJapan Animal Specialty Medical Institute, Tsuzuki, Yokohama, Japan.
Hiroshi SugiyaJapan Animal Specialty Medical Institute, Tsuzuki, Yokohama, Japan.
Masami UechiJapan Animal Specialty Medical Institute, Tsuzuki, Yokohama, Japan.
RIKEN Center for Integrative Medical Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac fibroblasts participate in the inflammatory process of heart diseases as sentinel cells of the cardiac tissue. In this study, we investigated the effect of the proinflammatory cytokine, interleukin 1β (IL-1β), on the expression of interleukin 8 (IL-8), which contributes to the induction of innate immunity

Indexed as

Interleukin-8NF-kappa BAnimalsDogsFibroblastsInterleukin-1betaRNA, MessengerRNA, Small InterferingInterleukin-1betaInterleukin-8NF-kappa BRNA, MessengerRNA, Small Interferingcardiac fibroblastsinflammationinterleukin 1βinterleukin 8NF-κB p65

Identifiers

PMID35514973
PMCPMC9065446
OpenAlexW4224236626

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.