Evidence map›Paper›PMID 35516837›Full record

ArticleJournal of toxicologic pathology2022

Testicular alterations in cryptorchid/orchiopexic rats chronically exposed to acrylamide or di-butyl-phthalate.

Thania R R Lima, Nathália P Souza, Ana P Ferragut Cardoso, Lígia M M Gomide, Merielen G Nascimento E Pontes, Hélio A Miot, Lora L Arnold, Samuel M Cohen, João Lauro V de Camargo

Open access · diamondAbstract read
In one paragraph

Article in Journal of toxicologic pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Thania R R LimaCenter for Evaluation of Environmental Impact on Human Health (TOXICAM), Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, 18618-687, São Paulo, Brazil.
Nathália P SouzaCenter for Evaluation of Environmental Impact on Human Health (TOXICAM), Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, 18618-687, São Paulo, Brazil.
Ana P Ferragut CardosoCenter for Evaluation of Environmental Impact on Human Health (TOXICAM), Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, 18618-687, São Paulo, Brazil.
Lígia M M GomideCenter for Evaluation of Environmental Impact on Human Health (TOXICAM), Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, 18618-687, São Paulo, Brazil.
Merielen G Nascimento E PontesCenter for Evaluation of Environmental Impact on Human Health (TOXICAM), Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, 18618-687, São Paulo, Brazil.
Hélio A MiotDepartment of Dermatology and Radiotherapy, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, 18618-687, São Paulo, Brazil.
Lora L ArnoldDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, 68105, NE, USA.
Samuel M CohenDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, 68105, NE, USA.
João Lauro V de CamargoCenter for Evaluation of Environmental Impact on Human Health (TOXICAM), Department of Pathology, Botucatu Medical School, São Paulo State University (UNESP), Botucatu, 18618-687, São Paulo, Brazil.
Universidade Estadual Paulista (Unesp) · BRUniversity of Nebraska Medical Center · USUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure of Sprague-Dawley (SD) rats to acrylamide (AA) or di-butyl-phthalate (DBP) from the 12th gestational day to the 16th postnatal week (PNW) has been shown to reduce the effectiveness of orchiopexy in recovering the testicular alterations associated with experimental cryptorchidism established at weaning. Herein, we provide information about the long-term effects of AA or DBP on the testes of cryptorchid/orchiopexic rats. Male offspring exposed

Indexed as

acrylamidechronic toxicitydi-butyl-phthalateorchiopexyrat surgical cryptorchidismtesticular germ cells

Identifiers

PMID35516837
PMCPMC9018398
OpenAlexW4226345306

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.