Evidence map›Paper›PMID 35519826›Full record

ArticleHGG advances2022

Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas.

Guojie Zhong, Priyanka Ahimaz, Nicole A Edwards, Jacob J Hagen, Christophe Faure, Qiao Lu, Paul Kingma, William Middlesworth, Julie Khlevner, Mahmoud El Fiky and 8 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in HGG advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Primary cilia are critical for tracheoesophageal septation.Developmental dynamics : an official publication of the American Association of Anatomists · 2024
    Article
  6. Article
  7. Statistical models of the genetic etiology of congenital heart disease.Current opinion in genetics & development · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Guojie ZhongDepartment of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.
Priyanka AhimazDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Nicole A EdwardsCenter for Stem Cell & Organoid Medicine (CuSTOM), Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Jacob J HagenDepartment of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.
Christophe FaureDivision of Pediatric Gastroenterology, CHU Sainte-Justine, Montreal, QC, Canada.
Qiao LuDepartment of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.
Paul KingmaDivision of Neonatology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
William MiddlesworthDivision of Pediatric Surgery, Columbia University Irving Medical Center, New York, NY, USA.
Julie KhlevnerDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Columbia University Irving Medical Center, New York, NY, USA.
Mahmoud El FikyPediatric Surgery, Faculty of Medicine, Cairo University, Cairo, Egypt.
David SchindelDivision of Pediatric Surgery, UT Southwestern School of Medicine Dallas, Texas, USA.
Elizabeth FialkowskiDivision of Pediatric Surgery, Oregon Health and Science University, Portland, OR, USA.
Adhish KashyapCenter for Stem Cell & Organoid Medicine (CuSTOM), Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Sophia ForlenzaDivision of Neonatology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Alan P KennyDivision of Neonatology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Aaron M ZornCenter for Stem Cell & Organoid Medicine (CuSTOM), Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH, USA.
Yufeng ShenDepartment of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.
Wendy K ChungDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Columbia University Irving Medical Center · USCincinnati Children's Hospital Medical Center · USBaylor School · USCairo University · EGCentre Hospitalier Universitaire Sainte-Justine · CAOregon Health & Science University · US

Funding

Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI LEE ARMISTEAD DENSON · 2007 to 2026
$24.4M
Project-3: Modeling EA/TEF in human organoidsP01HD093363 · NICHD · CINCINNATI CHILDRENS HOSP MED CTR · PI Wendy K Chung, Paul scot Kingma · 2017 to 2026
$16.2M
Integrate cancer genomics data in geneticstudies and diagnosis of developmental disordersR01GM120609 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEN, YUFENG · 2017 to 2021
$1.7M
Integrate gene expression data to characterize the contribution of rare genetic risk factors to structural birth defectsR03HL147197 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEN, YUFENG · 2019 to 2020
$315k
NHLBI NIH HHS R03 HL147197NICHD NIH HHS P01 HD093363NIDDK NIH HHS P30 DK078392NIGMS NIH HHS R01 GM120609
6 · The paper itself

Abstract

Esophageal atresias/tracheoesophageal fistulas (EA/TEF) are rare congenital anomalies caused by aberrant development of the foregut. Previous studies indicate that rare or

Indexed as

aerodigestivecongenital anomalyesophageal atresiatracheoesophageal fistulaXenopus

Identifiers

PMID35519826
PMCPMC9065433
OpenAlexW4224035361

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.