ReviewRSC advances2020
Molecularly imprinted polymer-based bioelectrical interfaces with intrinsic molecular charges.
Review in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 31 citations in OpenAlex.
- Review
- Signal transduction interfaces for field-effect transistor-based biosensors.Communications chemistry · 2024Review
- Article
- Molecular Level Sucrose Quantification: A Critical Review.Sensors (Basel, Switzerland) · 2022Review
- Article
- Technical Perspectives on Applications of Biologically Coupled Gate Field-Effect Transistors.Sensors (Basel, Switzerland) · 2022Article
- Self-oscillating chemoelectrical interface of solution-gated ion-sensitive field-effect transistor based on Belousov-Zhabotinsky reaction.Scientific reports · 2022Article
- Electrochemically Deposited Molecularly Imprinted Polymer-Based Sensors.Sensors (Basel, Switzerland) · 2022Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For enzyme-/antibody-free and label-free biosensing, a molecularly imprinted polymer (MIP)-based membrane with phenylboronic acid (PBA) molecules, which induces the change in the density of molecular charges based on the small biomolecule-PBA diol binding, has been demonstrated to be suitable for the bioelectrical interface of biologically coupled gate field-effect transistor (bio-FET) sensors. MIP-coated gate FET sensors selectively detect various small biomolecules such as glucose, dopamine, sialic acid, and oligosaccharides without using labeled materials. In particular, the well-controlled MIP film by surface-initiated atom transfer radical polymerization (SI-ATRP) contributes to the quantitative analysis of small biomolecule sensing, resulting in potentiometric Langmuir isotherm adsorption analysis by which the parameters such as the binding affinity between small biomolecules and MIP cavities are evaluated. Also, the output electrical signal of even a random MIP-coated gate FET sensor is quantitatively analyzed using the bi-Langmuir adsorption isotherm equation, showing the adsorption mechanism of small biomolecules onto the template-specific MIP membrane. Thus, a platform based on the MIP bioelectrical interface for the bio-FET sensor is suitable for an enzyme-/antibody-free and label-free biosensing system in the fields of clinical diagnostics, drug discovery, the food industry, and environmental research.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.