Evidence map›Paper›PMID 35525911›Full record

ArticleTropical animal health and production2022

Selection signatures in melanocortin-1 receptor gene of turkeys (Meleagris gallopavo) raised in hot humid tropics.

S O Durosaro, B M Ilori, O S Iyasere, O G George, O A Adewumi, P A Ojo, T A Yusuff, M R Adetifa, T S Atanda, M O Ozoje

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Article in Tropical animal health and production, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

S O DurosaroDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria. durosaroso@funaab.edu.ng.ORCID http://orcid.org/0000-0002-2613-3026
B M IloriDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
O S IyasereDepartment of Animal Physiology, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
O G GeorgeDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
O A AdewumiDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
P A OjoDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
T A YusuffDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
M R AdetifaDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
T S AtandaDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
M O OzojeDepartment of Animal Breeding and Genetics, Federal University of Agriculture, P.M.B, Abeokuta, Ogun State, 2240, Nigeria.
Federal University of Agriculture · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feather colours are used by avian species for defense, adaptation and signaling. Melanocortin-1 receptor (MC1R) gene is one of the genes responsible for feather colour. This study identified selection signatures in MC1R gene of Nigerian indigenous turkeys (NIT) using British United turkeys (BUT) as control breed to investigate the evolutionary processes that have shaped NIT with various feather colours. Complete MC1R gene of 146 NIT (76 males and 70 females) and 32 BUT (18 males and 14 females) were sequenced. Transition/transversion and codon usage biases were predicted using MEGA v6 software. The selective force acting on the gene was predicted using HyPhy software. The FST values were estimated using Arlequin v3.5. The highest transition/transversion bias was predicted for white BUT (1.00) while the lowest was predicted for black NIT (0.50). Negative dN-dS values, indicative of purifying selection, were observed in MC1R gene of all the turkeys. The highest pairwise FST was observed between the MC1R gene of white BUT and black NIT while the least was observed between lavender NIT and white NIT. No recombination event was observed in black NIT and white BUT. The relative synonymous codon usage was the same among different colours for some codons. Presence of purifying selection in MC1R gene of all the turkeys with different feather colours confirms that the gene plays role in many biological processes such as feather colouration, behaviour, pain perception, immunity, growth and adaptation. The results also suggested that the genetic mechanisms generating different feather colours in turkeys are conserved.

Indexed as

Receptor, Melanocortin, Type 1TurkeysAnimalsBase SequenceFeathersFemaleMalePlant BreedingReceptor, Melanocortin, Type 1Codon usagePurifying selectionRecombinationTransitionTransversion

Identifiers

PMID35525911
OpenAlexW4229041806

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.