Evidence map›Paper›PMID 35528164›Full record

ArticleBioMed research international2022

Molecular Hydrogen Inhibits Colorectal Cancer Growth via the AKT/SCD1 Signaling Pathway.

Xiangyan Zhang, Geru Tao, Ya'nan Zhao, Sijie Xing, Jie Jiang, Boyan Liu, Shucun Qin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiangyan ZhangDepartment of Pathophysiology, Basic Medicine College, Qingdao University, Qingdao 266000, China.ORCID https://orcid.org/0000-0002-0134-3414
Geru TaoThe Second Affiliated Hospital of Shandong First Medical University, Tai'an 271000, China.
Ya'nan ZhaoThe Second Affiliated Hospital of Shandong First Medical University, Tai'an 271000, China.
Sijie XingThe Second Affiliated Hospital of Shandong First Medical University, Tai'an 271000, China.
Jie JiangThe Second Affiliated Hospital of Shandong First Medical University, Tai'an 271000, China.
Boyan LiuThe Second Affiliated Hospital of Shandong First Medical University, Tai'an 271000, China.
Shucun QinDepartment of Pathophysiology, Basic Medicine College, Qingdao University, Qingdao 266000, China.ORCID https://orcid.org/0000-0002-2318-8080
Affiliated Hospital of Taishan Medical University · CNQingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Molecular hydrogen (H Methods: The effect of H Results: Hydrogen treatment suppressed the proliferation of CRC cell lines independent of apoptosis, and the cell lines showed different responses to different doses of H Conclusion: This study demonstrates that high concentrations of H

Indexed as

Colorectal NeoplasmsProto-Oncogene Proteins c-aktAnimalsApoptosisCell Line, TumorCell ProliferationGene Expression Regulation, NeoplasticHumansHydrogenMicePhosphatidylinositol 3-KinasesSignal TransductionStearoyl-CoA DesaturaseHydrogenPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSCD1 protein, humanScd1 protein, mouseStearoyl-CoA Desaturase

Identifiers

PMID35528164
PMCPMC9071919
OpenAlexW4224923132

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.