Evidence map›Paper›PMID 35528587›Full record

ArticleRSC advances2019

A marine sponge associated fungal metabolite monacolin X suppresses angiogenesis by down regulating VEGFR2 signaling.

Sirpu Natesh Nagabhishek, Arumugam Madan Kumar, Sambhavi B, Anandan Balakrishnan, Yash T Katakia, Suvro Chatterjee, Nagarajan Nagasundaram

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 5 countries.

Sirpu Natesh NagabhishekCancer Biology Lab, Molecular and Nanomedicine Research Unit, Sathyabama Institute of Science and Technology Chennai-600 119 Tamil Nadu India madankumarbio@gmail.com madankumar@sathyabama.ac.in +91 9942110146.ORCID https://orcid.org/0000-0003-3826-1591
Arumugam Madan KumarCancer Biology Lab, Molecular and Nanomedicine Research Unit, Sathyabama Institute of Science and Technology Chennai-600 119 Tamil Nadu India madankumarbio@gmail.com madankumar@sathyabama.ac.in +91 9942110146.ORCID https://orcid.org/0000-0003-0567-7857
Sambhavi BDepartment of Genetics, Dr ALM PGIBMS University of Madras Taramani Chennai Tamil Nadu India.
Anandan BalakrishnanDepartment of Genetics, Dr ALM PGIBMS University of Madras Taramani Chennai Tamil Nadu India.
Yash T KatakiaVascular Biology Lab, AU-KBC Research Centre, Department of Biotechnology, Anna University Chennai Tamil Nadu India.
Suvro ChatterjeeVascular Biology Lab, AU-KBC Research Centre, Department of Biotechnology, Anna University Chennai Tamil Nadu India.ORCID https://orcid.org/0000-0003-4413-9760
Nagarajan NagasundaramSchool of Humanities, Nanyang Technological University 14 Nanyang Dr Singapore.
Anna University, Chennai · INNanomed (Brazil) · BRUniversity of Madras · INNanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the leading causes of global death and there is an urgent need for the development of cancer treatment; targeting VEGFR2 could be one of the promising therapies. In the present study, previously isolated marine fungal metabolite monacolin X, suppresses

Identifiers

PMID35528587
PMCPMC9070443
OpenAlexW2970471762

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.