ReviewAnnual review of clinical psychology2022
Allostasis, Action, and Affect in Depression: Insights from the Theory of Constructed Emotion.
Review in Annual review of clinical psychology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- Mechanistic studies in pathological health anxiety: A systematic review and emerging conceptual framework.Journal of affective disorders · 2024Pooled it
- Modality-specific reactive and predictive responses in the human superior colliculus.Nature neuroscience · 2026Article
- Adolescent mental health outcomes following early regulatory problems.European child & adolescent psychiatry · 2026Article
- Putting Emotional Memories in Context: The Constructionist Model of Emotional Memory.Perspectives on psychological science : a journal of the Association for Psychological Science · 2026Review
- Emotions Are Folk Concepts in a Predicting Brain.Brain sciences · 2026Article
- Categorization is 'baked' into the brain.Nature reviews. Neuroscience · 2026Review
- The priming effect of interoception on savoring positive emotion: An EEG study.Cognitive, affective & behavioral neuroscience · 2026Article
- Altered gray matter volume in major depressive disorder patients with psychomotor retardation.Neuroreport · 2026Article
- Sleep in Functional Motor Disorders: A Case-Control Polysomnographic Study.Journal of sleep research · 2026Article
- Brain Changes Underlying Irritable Bowel Syndrome Symptom Improvement in Response to Mindfulness-Based Stress Reduction.Neurogastroenterology and motility · 2026Article
- The inadequacy of normative ratings for building stimulus sets in affective science.Emotion (Washington, D.C.) · 2026Article
- Review
- Cortical and subcortical mapping of the human allostatic-interoceptive system using 7 Tesla fMRI.Nature neuroscience · 2025Article
- An interoceptive model of energy allostasis linking metabolic and mental health.Science advances · 2025Review
- Disorder at the Synapse: How the Active Inference Framework Unifies Competing Perspectives on Depression.Entropy (Basel, Switzerland) · 2025Review
- The 4Rs Framework of Sports Nutrition: An Update with Recommendations to Evaluate Allostatic Load in Athletes.Life (Basel, Switzerland) · 2025Review
- Pilot Testing an Ecotherapy Program for Adolescence: Initial Findings and Methodological Reflections.International journal of environmental research and public health · 2025Article
- Everyday emotion-goal pursuit associations in older adults are moderated by goal representations.Communications psychology · 2025Article
- Towards an expanded neurocognitive account of ketamine's rapid antidepressant effects.The international journal of neuropsychopharmacology · 2025Review
- Exploring the impact of maternal early life adversity on interoceptive sensibility in pregnancy: implications for prenatal depression.Archives of women's mental health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The theory of constructed emotion is a systems neuroscience approach to understanding the nature of emotion. It is also a general theoretical framework to guide hypothesis generation for how actions and experiences are constructed as the brain continually anticipates metabolic needs and attempts to meet those needs before they arise (termed allostasis). In this review, we introduce this framework and hypothesize that allostatic dysregulation is a trans-disorder vulnerability for mental and physical illness. We then review published findings consistent with the hypothesis that several symptoms in major depressive disorder (MDD), such as fatigue, distress, context insensitivity, reward insensitivity, and motor retardation, are associated with persistent problems in energy regulation. Our approach transforms the current understanding of MDD as resulting from enhanced emotional reactivity combined with reduced cognitive control and, in doing so, offers novel hypotheses regarding the development, progression, treatment, and prevention of MDD.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.