Evidence map›Paper›PMID 35535397›Full record

ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

D-dimer to Creatinine Ratio: A Novel Biomarker Associated with Gensini Score in ST-Segment Elevation Myocardial Infarction Patients.

Jiaojiao Yang, Yingjie Zhao, Yong Li, Jianmin Tang, Yipin Zhao

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Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jiaojiao YangDepartment of Gastroenterology, Songjiang Hospital Affiliated to Shanghai Jiao Tong University School of Medicine (Preparatory Stage), Shanghai, China.
Yingjie ZhaoDepartment of Cardiology, 569063The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yong LiThe Fourth Department of Cardiology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.
Jianmin TangDepartment of Cardiology, 569063The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yipin ZhaoDepartment of Cardiology, 569063The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID https://orcid.org/0000-0003-1446-1273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe propose for the first time that D-dimer to creatinine ratio (DCR) may serve as a new clinical biomarker and explore its association with ST-segment elevation myocardial infarction (STEMI).

methods347 STEMI patients with complete D-dimer and creatinine were included in the analysis. According to the median of DCR value, patients were divided into the lower DCR group (DCR < 1.402, n = 173) and the higher DCR group (DCR ≥ 1.402, n = 174), and the differences between the two groups were compared. In addition, patients were divided into four groups according to the quartiles of Gensini score: Group 1(Gensini score ≤ 34, n = 88); Group 2(34 < Gensini score ≤ 65, n = 88); Group 3(65 < Gensini score ≤100, n = 87); Group 4(Gensini score ＞100, n = 84). Multivariate linear and multivariate logistic regression analyzes were performed to determine independent predictors of the Gensini score.

resultsHigh DCR group had higher Gensini score compared with the low DCR group (

conclusionsAs a new and useful clinical biomarker, DCR was positively correlated with coronary Gensini score in STEMI patients.

Indexed as

ST Elevation Myocardial InfarctionBiomarkersCreatinineFibrin Fibrinogen Degradation ProductsHumansRisk FactorsBiomarkersCreatinineFibrin Fibrinogen Degradation Productsfibrin fragment DcreatinineD-dimerD-dimer to creatinine ratioGensini scoreST-elevation myocardial infarction

Identifiers

PMID35535397
PMCPMC9096193

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.