Evidence map›Paper›PMID 35538242›Full record

Trial reportEuropean journal of applied physiology2022

Different exercise training modalities similarly improve heart rate variability in sedentary middle-aged adults: the FIT-AGEING randomized controlled trial.

Ginés Navarro-Lomas, Manuel Dote-Montero, Juan M A Alcantara, Abel Plaza-Florido, Manuel J Castillo, Francisco J Amaro-Gahete

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03334357 (Physical Fitness as Klotho Protein Stimulator; Antiaging Effects of New Training Methods), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03334357 nacompletednot on this map

Physical Fitness as Klotho Protein Stimulator; Antiaging Effects of New Training Methods (FIT-AGING).

TypeinterventionalSponsorManuel Castillo GarzónRan2016 to 2017Enrolled74ConditionsPhysical Activity, AgingArmsPAR, HIIT, WB-EMS
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ginés Navarro-LomasEFFECTS-262 Research Group, Department of Physiology, Faculty of Medicine, University of Granada, Avda. de la Investigación 11, 18016, Granada, Spain. ginesnl1@gmail.com.ORCID http://orcid.org/0000-0002-9995-3455
Manuel Dote-MonteroEFFECTS-262 Research Group, Department of Physiology, Faculty of Medicine, University of Granada, Avda. de la Investigación 11, 18016, Granada, Spain.ORCID http://orcid.org/0000-0003-0715-8620
Juan M A Alcantara1 PROmoting FITness and Health Through Physical Activity Research Group (PROFITH), Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, Camino de Alfacar s/n, 18071, Granada, Spain.ORCID http://orcid.org/0000-0002-8842-374X
Abel Plaza-Florido1 PROmoting FITness and Health Through Physical Activity Research Group (PROFITH), Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, Camino de Alfacar s/n, 18071, Granada, Spain.ORCID http://orcid.org/0000-0002-5374-3129
Manuel J CastilloEFFECTS-262 Research Group, Department of Physiology, Faculty of Medicine, University of Granada, Avda. de la Investigación 11, 18016, Granada, Spain.ORCID http://orcid.org/0000-0002-1196-9488
Francisco J Amaro-GaheteEFFECTS-262 Research Group, Department of Physiology, Faculty of Medicine, University of Granada, Avda. de la Investigación 11, 18016, Granada, Spain. amarof@ugr.es.ORCID http://orcid.org/0000-0002-7207-9016
Universidad de Granada · ES

Funding

Spanish Ministry of Education FPU14/04172Spanish Ministry of Education FPU16/02760Spanish Ministry of Education FPU18/03357University of Granada Plan Propio de Investigación 2020 Programa de Contratos Puente
6 · The paper itself

Abstract

purposeThis study aimed to investigate the influence of different exercise training modalities on heart rate variability (HRV) in sedentary middle-aged adults; and to study whether changes in health-related outcomes (i.e., body composition and cardiometabolic risk) are associated with those hypothetical HRV changes in sedentary middle-aged adults.

methodsA total of 66 middle-aged adults (53.6 ± 4.4 years old; 50% women) were enrolled in the FIT-AGEING study. We conducted a 12-week randomized controlled trial. The participants were randomly assigned to 4 groups: (a) a control group (no exercise); (b) a physical activity recommendation from the World Health Organization group (PAR); (c) a high-intensity interval training group (HIIT); and (d) a high-intensity interval training group adding whole-body electromyostimulation (HIIT + EMS).

resultsAll exercise training modalities induced changes in HRV parameters (all P ≤ 0.001) without statistical differences between them (all P > 0.05). We found associations between changes in body composition and cardiometabolic risk and exercise-related changes in HRV.

conclusionOur results suggest that different exercise interventions (i.e., PAR, HIIT and HIIT + EMS) induced an enhancement of HRV in sedentary middle-aged adults. Our findings support the notion that exercise-related changes in HRV are associated with changes in body composition and cardiometabolic risk after the intervention program CLINICAL TRIAL REGISTRY: NCT03334357 (ClinicalTrials.gov). November 7, 2017 retrospectively registered.

Indexed as

Cardiovascular DiseasesHigh-Intensity Interval TrainingAdultBody CompositionExerciseFemaleHeart RateHumansMaleMiddle AgedAutonomic nervous systemCardiometabolic healthTrainingVagal activity, physical activity

Identifiers

PMID35538242
PMCPMC9287234
OpenAlexW4280580440

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.