Evidence map›Paper›PMID 35539266›Full record

ArticleRSC advances2018

Humanization and directed evolution of the selenium-containing

Yan Xu, Pengju Li, Jiaojiao Nie, Qi Zhao, Shanshan Guan, Ziyu Kuai, Yongbo Qiao, Xiaoyu Jiang, Ying Li, Wei Li and 3 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 3 countries.

Yan XuNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Pengju LiNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Jiaojiao NieNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Qi ZhaoFaculty of Health Sciences, University of Macau Macau China.ORCID https://orcid.org/0000-0002-5969-6407
Shanshan GuanNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Ziyu KuaiNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Yongbo QiaoNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Xiaoyu JiangNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Ying LiNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Wei LiNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Yuhua ShiNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Wei KongNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.
Yaming ShanNational Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University Changchun Jilin China shanym@jlu.edu.cn +86 431 85167751 +86 431 89228979.ORCID https://orcid.org/0000-0001-8373-6088
Jilin University · CNUniversity of Macau · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the binding site structure and the catalytic mechanism of the native glutathione peroxidase (GPX), three glutathione derivatives, GSH-S-DNP butyl ester (hapten Be), GSH-S-DNP hexyl ester (hapten He) and GSH-S-DNP hexamethylene ester (hapten Hme) were synthesized. By a four-round panning with a human synthetic

Identifiers

PMID35539266
PMCPMC9080455
OpenAlexW2801858392

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.