Evidence map›Paper›PMID 35545672›Full record

ArticleNature2022

Olfactory sensory experience regulates gliomagenesis via neuronal IGF1.

Pengxiang Chen, Wei Wang, Rui Liu, Jiahui Lyu, Lei Zhang, Baizhou Li, Biying Qiu, Anhao Tian, Wenhong Jiang, Honggang Ying and 7 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 1 pooled it
16.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. Pooled it
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  16. Dysregulated Microglial Synaptic Engulfment in Diffuse Midline Glioma.bioRxiv : the preprint server for biology · 2025
    Article
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27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Pengxiang ChenDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.ORCID http://orcid.org/0000-0002-7660-4981
Wei WangDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Rui LiuDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Jiahui LyuInstitute for Translational Brain Research, MOE Frontiers Center for Brain Science, Fudan University, Shanghai, P.R. China.
Lei ZhangDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Baizhou LiDepartment of Pathology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Biying QiuDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Anhao TianDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Wenhong JiangDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Honggang YingDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Rui JingDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Qianqian WangLaboratory Animal Center of Zhejiang University, Hangzhou, P.R. China.
Keqing ZhuDepartment of Pathology and Pathophysiology, Zhejiang University School of Medicine, Hangzhou, P.R. China.
Ruiliang BaiDepartment of Physical Medicine and Rehabilitation of The Affiliated Sir Run Shumen Shaw Hospital and Interdisciplinary Institute of Neuroscience and Technology, Zhejiang University School of Medicine, Hangzhou, P.R. China.ORCID http://orcid.org/0000-0003-4246-5984
Linghui ZengDepartment of Pharmacology, School of Medicine, Zhejiang University City College, Hangzhou, P.R. China.
Shumin DuanDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China.ORCID http://orcid.org/0000-0002-0466-1821
Chong LiuDepartment of Neurobiology and Department of Neurosurgery of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China. chongliu77@zju.edu.cn.ORCID http://orcid.org/0000-0001-6578-5919
Second Affiliated Hospital of Zhejiang University · CNZhejiang University · CNFudan University · CNAllen Institute for Brain Science · USSir Run Run Shaw Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Animals constantly receive various sensory stimuli, such as odours, sounds, light and touch, from the surrounding environment. These sensory inputs are essential for animals to search for food and avoid predators, but they also affect their physiological status, and may cause diseases such as cancer. Malignant gliomas-the most lethal form of brain tumour

Indexed as

CarcinogenesisGliomaInsulin-Like Growth Factor IOlfactory Receptor NeuronsSmellAnimalsMiceNeural PathwaysOlfactory Bulbinsulin-like growth factor-1, mouseInsulin-Like Growth Factor I

Identifiers

PMID35545672
OpenAlexW4280613307

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.