ArticleBMC endocrine disorders2022
Body mass index at baseline directly predicts new-onset diabetes and to a lesser extent incident cardio-cerebrovascular events, but has a J-shaped relationship to all-cause mortality.
Article in BMC endocrine disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Using artificial intelligence to predict adverse outcomes in emergency department patients with hyperglycemic crises in real time.BMC endocrine disorders · 2023Trial
- Body roundness index shows a short-term, sex-specific advantage over body mass index in predicting incident diabetes: a longitudinal prospective cohort study.Journal of endocrinological investigation · 2026Article
- Effect of body mass index change on the development of diabetes mellitus.Endocrine journal · 2026Article
- Association of relative fat mass (RFM) index with diabetes-related mortality and heart disease mortality.Scientific reports · 2024Article
- Overweight and obesity as risk factors for chronic low back pain: a new follow-up in the HUNT Study.BMC public health · 2024Article
- Association of body indices and risk of mortality in patients with type 2 diabetes.BMJ open diabetes research & care · 2023Article
- Correlation of Obesity and Overweight with Cervical Vascular Function Among Healthy Populations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe prevalence of diabetes mellitus (DM), cardio-cerebrovascular diseases (CCVDs) has increased during recent decades. We aimed to investigate the relationship between body mass index (BMI) and each of several outcomes (DM, CCVDs, or mortality) based on the Korean National Health Insurance Service-Health Screening cohort.
methodsBMI was categorized as appropriate for Asian populations, into underweight (< 18.5 kg/m
resultsA total of 311,416 individuals were included. The median follow-up was 12.5 years. Compared to normal BMI, underweight, overweight, and grade 1-3 obese individuals had a higher risk of the primary outcomes (hazard ratio [95% confidence intervals] 1.293 [1.224-1.365], 1.101 [1.073-1.129], 1.320 [1.288-1.353], 1.789 [1.689-1.897], and 2.376 [2.019-2.857], respectively, in men and 1.084 [1.010-1.163], 1.150 [1.116-1.185], 1.385 [1.346-1.425], 1.865 [1.725-2.019], and 2.472 [2.025-3.028], respectively, in women). Setting the reference BMI to 20-< 21 kg/m
conclusionsBMI was associated with all-cause mortality in a J-shaped manner in both sexes, while it was associated with risk of DM in a dose-response relationship. The relationship between BMI and the primary outcomes was J-shaped.
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