Evidence map›Paper›PMID 35546576›Full record

ArticleMicrobiology spectrum2022

Genetic Structure and Triazole Antifungal Susceptibilities of Alternaria alternata from Greenhouses in Kunming, China.

Guangzhu Yang, Sai Cui, Nan Ma, Yuansha Song, Jun Ma, Wenjing Huang, Ying Zhang, Jianping Xu

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. First Reported Case of a Clinically Nonresponsive-to-ItraconazoleJournal of fungi (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Guangzhu YangState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan Universitygrid.440773.3, Kunming, People's Republic of China.
Sai CuiSchool of Life Science, Yunnan Universitygrid.440773.3, Kunming, People's Republic of China.
Nan MaState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan Universitygrid.440773.3, Kunming, People's Republic of China.
Yuansha SongState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan Universitygrid.440773.3, Kunming, People's Republic of China.
Jun MaHorticultural Research Institute, Yunnan Academy of Agricultural Sciences, Kunming, People's Republic of China.
Wenjing HuangHorticultural Research Institute, Yunnan Academy of Agricultural Sciences, Kunming, People's Republic of China.
Ying ZhangState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan Universitygrid.440773.3, Kunming, People's Republic of China.
Jianping XuState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan Universitygrid.440773.3, Kunming, People's Republic of China.ORCID 0000-0003-2915-2780
Yunnan University · CNYunnan Academy of Agricultural Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alternaria alternata is an opportunistic human fungal pathogen and a ubiquitous phytopathogen capable of causing diseases to >100 agricultural crops and ornamental plants. To control plant diseases caused by A. alternata, triazole fungicides have been widely used both in open crop and vegetable fields and in indoor growth facilities such as greenhouses. At present, the effect of fungicide use on triazole resistance development in A. alternata populations is not known. Here, we isolated 237 A. alternata strains from nine greenhouses around metropolitan Kunming in Yunnan, southwest China, determined their genotypes using 10 short tandem repeat markers, and quantified their susceptibility to four triazoles (difenoconazole, tebuconazole, itraconazole, and voriconazole). Abundant allelic and genotypic diversities were detected among these A. alternata strains. Significantly, over 17% of the strains were resistant to difenoconazole, and both known and new drug-resistance mutations were found in the triazole target gene

Indexed as

Antifungal AgentsFungicides, IndustrialAlternariaChinaDrug Resistance, FungalGenetic StructuresHumansTriazolesAntifungal AgentsFungicides, IndustrialTriazolesallelic diversitycyp51genetic differentiationhuman fungal pathogenplant fungal pathogenpopulation geneticsshort tandem repeatstriazole resistance

Identifiers

PMID35546576
PMCPMC9241833
OpenAlexW4280603927

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.