Evidence map›Paper›PMID 35547343›Full record

ArticleIndian journal of orthopaedics2022

Parameter Optimization for Printing Ti6Al4V-Alloy Patient-Customized Orthopaedic Implants by Laser Powder Bed Fusion Using Physio-mechanical Properties and Biological Evaluations.

Bhanupratap Gaur, Rupesh Ghyar, Ravi Bhallamudi

Abstract read
In one paragraph

Article in Indian journal of orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bhanupratap GaurBiomedical Engineering and Technology Innovation Centre (BETIC) Lab, Mechanical Engineering Department, Indian Institute of Technology Bombay, Powai, Mumbai, Maharashtra 400076 India.ORCID 0000-0003-3662-5048
Rupesh GhyarBiomedical Engineering and Technology Innovation Centre (BETIC) Lab, Mechanical Engineering Department, Indian Institute of Technology Bombay, Powai, Mumbai, Maharashtra 400076 India.
Ravi BhallamudiBiomedical Engineering and Technology Innovation Centre (BETIC) Lab, Mechanical Engineering Department, Indian Institute of Technology Bombay, Powai, Mumbai, Maharashtra 400076 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: A class of additive manufacturing technologies called Laser powder bed fusion (LPBF), which allows fabricating metallic components with complex geometries in near-net-shape, can be employed for fabricating patient-customized orthopaedic implants. Selection and optimization of the LPBF process parameters are critical to achieving the required biomechanical properties and fabricability of such implants. Methods: The process parameters of direct metal laser sintering, the most widely used LPBF process, were optimized for fabricating Ti6Al4V ELI orthopaedic implants, based on ASTM and ASM standards. The parameters included Laser power, Laser velocity and hatch distance, which were varied using Taguchi approach. A multi-criteria decision-making technique (TOPSIS) was employed to optimize the process parameters considering yield and ultimate tensile strength, percentage elongation, part density, volumetric energy density and printing time. In-vitro cytotoxicity and in-vivo muscle implantation were performed on the optimized samples for determining the suitability of the parameters for biomedical applications. Results: A combination of medium laser power, higher laser velocity, and lower hatch distance with values 200 W, 2200 mm/s and 0.08 mm, respectively, was found to be suitable for producing implants. Based on the type of LPBF technology in use, an implant manufacturer can select the initial set of parameters using a similar approach and improve them further based on experimental results. Conclusion: The optimized parameters were found to be suitable for developing orthopaedic implants, in terms of physical, mechanical and biological criteria. The methods and results presented in work are expected to assist the implant manufacturers in meeting the expected user requirements and quality standards. Graphical abstract:

Indexed as

Additive manufacturingDirect metal laser sinteringLaser powder bed fusionPatient-customized orthopaedic implantsProcess parameter optimization

Identifiers

PMID35547343
PMCPMC9043156

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.