Evidence map›Paper›PMID 35547630›Full record

ArticleFrontiers in aging neuroscience2022

Statistical Parametric Mapping in Amyloid Positron Emission Tomography.

Natasha M Smith, Jeremy N Ford, Arsalan Haghdel, Lidia Glodzik, Yi Li, Debra D'Angelo, Arindam RoyChoudhury, Xiuyuan Wang, Kaj Blennow, Mony J de Leon and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Medicare Coverage of Amyloid PET: Implications for Clinical Practice.AJNR. American journal of neuroradiology · 2023
    Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Natasha M SmithDepartment of Radiology and MD Program, Weill Cornell Medicine, New York City, NY, United States.
Jeremy N FordDepartment of Radiology, Weill Cornell Medicine, New York City, NY, United States.
Arsalan HaghdelDepartment of Radiology and MD Program, Weill Cornell Medicine, New York City, NY, United States.
Lidia GlodzikDepartment of Radiology, Weill Cornell Medicine, New York City, NY, United States.
Yi LiDepartment of Radiology, Weill Cornell Medicine, New York City, NY, United States.
Debra D'AngeloDepartment of Population Health Sciences, Weill Cornell Medicine, New York City, NY, United States.
Arindam RoyChoudhuryDepartment of Population Health Sciences, Weill Cornell Medicine, New York City, NY, United States.
Xiuyuan WangDepartment of Radiology, Weill Cornell Medicine, New York City, NY, United States.
Kaj BlennowDepartment of Neuroscience and Physiology, University of Gothenburg, Mölndal, Sweden.
Mony J de LeonDepartment of Radiology, Weill Cornell Medicine, New York City, NY, United States.
Jana IvanidzeDepartment of Radiology, Weill Cornell Medicine, New York City, NY, United States.
Weill Cornell Medicine · USCornell University · USMassachusetts General Hospital · USUniversity of Gothenburg · SE

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Research Education ComponentP30AG066512 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mary Sherman Mittelman · 2020 to 2026
$28.4M
CSF Clearance in Sporadic Alzheimer's DiseaseR01AG057848 · NIA · WEILL MEDICAL COLL OF CORNELL UNIV · PI LI, YI · 2018 to 2023
$4.0M
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NIA NIH HHS P30 AG066512NIA NIH HHS R01 AG057848
6 · The paper itself

Abstract

Alzheimer's disease (AD), the most common cause of dementia, has limited treatment options. Emerging disease modifying therapies are targeted at clearing amyloid-β (Aβ) aggregates and slowing the rate of amyloid deposition. However, amyloid burden is not routinely evaluated quantitatively for purposes of disease progression and treatment response assessment. Statistical Parametric Mapping (SPM) is a technique comparing single-subject Positron Emission Tomography (PET) to a healthy cohort that may improve quantification of amyloid burden and diagnostic performance. While primarily used in 2-[

Indexed as

Alzheimer’s diseaseamyloiddementiaPETSPM

Identifiers

PMID35547630
PMCPMC9083453
OpenAlexW4224729310

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.