ArticleFrontiers in nutrition2022
Evaluation and Screening of Hypoglycemic Activity of Total Ginsenosides GBE-5 Fraction From
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 5 citations in OpenAlex.
- Targeting ferroptosis: New perspectives of Chinese herbal medicine in the treatment of diabetes and its complications.Heliyon · 2023Review
- Effects of Ferroptosis on Cardiovascular Diseases.Mediators of inflammation · 2023Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
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Abstract
Objective: Ginseng berry (GB) was the mature fruit of medicinal and edible herb, Methods: The polar fractions of ginseng berry extract (GBE) were separated by a solvent extraction, and identified by ultra-high performance liquid chromatography-high-resolution mass spectrometry (UHPLC-MS). The insulin resistance model of HepG2 cells was established, and the hypoglycemic active fraction in GBE polar fractions were screened Results: It was found that GBE-5 fraction had better hypoglycemic activity than other GBE polar fractions Conclusions: The hypoglycemic effect of GBE-5 fraction was better than that of total ginsenoside of GB. The AA metabolism, LA metabolism, unsaturated fatty acid biosynthesis, and ferroptosis were the potential metabolic pathways for GBE-5 fraction to exert hypoglycemic regulation.
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