Evidence map›Paper›PMID 35558562›Full record

ReviewFrontiers in molecular biosciences2022

Functional and Structural Diversity of Bacterial Contact-Dependent Growth Inhibition Effectors.

Bonnie J Cuthbert, Christopher S Hayes, Celia W Goulding

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Pathogenicity assessment of Shiga toxin-producingFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bonnie J CuthbertMolecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, United States.
Christopher S HayesMolecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA, United States.
Celia W GouldingMolecular Biology and Biochemistry, University of California, Irvine, Irvine, CA, United States.
University of California, Irvine · USUniversity of California, Santa Barbara · US

Funding

Molecular Mechanisms of anti-bacterial contact-dependent growth inhibition (CDI)R01GM117930 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI HAYES, CHRISTOPHER S. · 2016 to 2023
$3.0M
Molecular mechanisms of antibacterial CDI toxin activationR01GM117373 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GOULDING, CELIA, HAYES, CHRISTOPHER S. · 2016 to 2019
$1.2M
Role of a novel auto-protease domain in antibacterial toxin deliveryR21AI159764 · NIAID · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI GOULDING, CELIA, HAYES, CHRISTOPHER S. · 2021 to 2022
$430k
NIGMS NIH HHS R01 GM117373NIGMS NIH HHS R01 GM117930
6 · The paper itself

Abstract

Bacteria live in complex communities and environments, competing for space and nutrients. Within their niche habitats, bacteria have developed various inter-bacterial mechanisms to compete and communicate. One such mechanism is contact-dependent growth inhibition (CDI). CDI is found in many Gram-negative bacteria, including several pathogens. These CDI

Indexed as

contact-dependent growth inhibitionstructuretoxin functiontoxin/immunity complextype V secretion system

Identifiers

PMID35558562
PMCPMC9086364
OpenAlexW4224847260

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.