ArticleEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology2022
Trajectory of cognitive impairments over 1 year after COVID-19 hospitalisation: Pattern, severity, and functional implications.
Article in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Cognitive domains affected post-COVID-19; a systematic review and meta-analysis.European journal of neurology · 2025Pooled it
- Comparison of Long COVID-19 Caused by Different SARS-CoV-2 Strains: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Post-COVID cognitive dysfunction in socioeconomically-vulnerable older adults: findings from a Brazilian cohort.Arquivos de neuro-psiquiatria · 2026Article
- Cognition, Cytokines, Blood-Brain Barrier, and Beyond in COVID-19: A Narrative Review.International journal of molecular sciences · 2026Review
- Cognitive and vascular (dys)function after COVID-19.Journal of neurovirology · 2025Article
- Optimization of a panel of behavioral tests for use in containment using a golden Syrian hamster model.Journal of virological methods · 2025Article
- Subjective cognitive, psychiatric, and fatigue symptoms two years after COVID-19: A prospective longitudinal cohort study.Brain, behavior, & immunity - health · 2025Article
- Cognitive Sequelae of COVID-19: Mechanistic Insights and Therapeutic Approaches.CNS neuroscience & therapeutics · 2025Review
- Cognitive outcomes and psychological symptoms in an Italian cohort with post-acute COVID-19 condition (PACC).Heliyon · 2024Article
- In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization.JAMA network open · 2024Article
- Neurocognitive and Neuropsychiatric Sequelae in Long COVID-19 Infection.Brain sciences · 2024Article
- Neurocognitive Changes in Patients with Post-COVID Depression.Journal of clinical medicine · 2024Article
- Cognitive and mental health trajectories of COVID-19: Role of hospitalisation and long-COVID symptoms.European psychiatry : the journal of the Association of European Psychiatrists · 2024Article
- "Brain Fog" After COVID-19 Infection: How the Field of Neuropsychology Can Help Clear the Air.Advances in experimental medicine and biology · 2024Article
- Cognitive impairment and neuropsychiatric symptoms among individuals with history of symptomatic SARS-CoV-2 infection: a retrospective longitudinal study.Dementia & neuropsychologia · 2024Article
- Evolving trends in neuropsychological profiles of post COVID-19 condition: A 1-year follow-up in individuals with cognitive complaints.PloS one · 2024Article
- Exploring cognitive impairments and the efficacy of phosphatidylcholine and computer-assisted cognitive training in post-acute COVID-19 and post-acute COVID-19 Vaccination Syndrome.Frontiers in neurology · 2024Article
- Cognitive impairment in post-acute COVID-19 syndrome: a scoping review.Arquivos de neuro-psiquiatria · 2023Article
- Brain Health After COVID-19, Pneumonia, Myocardial Infarction, or Critical Illness.JAMA network open · 2023Article
- Effect of oxygen therapy duration on cognitive impairment 12 months after hospitalization for SARS-COV-2 infection.Journal of rehabilitation medicine · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ongoing Coronavirus Disease (COVID-19) pandemic has so far affected more than 500 million people. Lingering fatigue and cognitive difficulties are key concerns because they impede productivity and quality of life. However, the prevalence and duration of neurocognitive sequelae and association with functional outcomes after COVID-19 are unclear. This longitudinal study explored the frequency, severity and pattern of cognitive impairment and functional implications 1 year after hospitalisation with COVID-19 and its trajectory from 3 months after hospitalisation. Patients who had been hospitalised with COVID-19 from our previously published 3-months study at the Copenhagen University Hospital were re-invited for a 1-year follow-up assessment of cognitive function, functioning and depression symptoms. Twenty-five of the 29 previously assessed patients (86%) were re-assessed after 1 year (11±2 months). Clinically significant cognitive impairments were identified in 48-56 % of patients depending on the cut-off, with verbal learning and executive function being most severely affected. This was comparable to the frequency of impairments observed after 3 months. Objectively measured cognitive impairments scaled with subjective cognitive difficulties, reduced work capacity and poorer quality of life. Further, cognitive impairments after 3 months were associated with the severity of subsequent depressive symptoms after 1 year. In conclusion, the stable cognitive impairments in approximately half of patients hospitalized with COVID-19 and negative implications for work functioning, quality of life and mood symptoms underline the importance of screening for and addressing cognitive sequelae after severe COVID-19.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.