Evidence map›Paper›PMID 35563009›Full record

ArticleInternational journal of molecular sciences2022

Enhanced cGMP Interactor Rap Guanine Exchange Factor 4 (EPAC2) Expression and Activity in Degenerating Photoreceptors: A Neuroprotective Response?

Michel Rasmussen, Jiaming Zhou, Frank Schwede, Per Ekström

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Michel RasmussenDepartment of Clinical Sciences Lund, Faculty of Medicine, Lund University, 22184 Lund, Sweden.ORCID 0000-0003-4932-8456
Jiaming ZhouDepartment of Clinical Sciences Lund, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Frank SchwedeBIOLOG Life Science Institute GmbH & Co. KG, 28199 Bremen, Germany.
Per EkströmDepartment of Clinical Sciences Lund, Faculty of Medicine, Lund University, 22184 Lund, Sweden.
Lund University · SEBiolog Life Science Institute · DE

Funding

European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie 765441Kronprinsessan Margaretas Arbetsnämnd för synskadade N/AÖgonfonden N/AStiftelsen för Synskadade i f.d. Malmöhus län N/AStiftelsen Landshövding Per Westlings minnesfond 95096The Royal Physiographic Society of Lund - the Natural Sciences, Medicine and Tech-nology - Medicine N/A
6 · The paper itself

Abstract

The disease retinitis pigmentosa (RP) leads to photoreceptor degeneration by a yet undefined mechanism(s). In several RP mouse models (i.e.,

Indexed as

Retinal DegenerationRetinitis PigmentosaAnimalsCyclic GMPDisease Models, AnimalGuanineMiceMice, Inbred C57BLRetinaCyclic GMPGuaninecAMPcGMPneuroprotectivephotoreceptorsrap guanine exchange factor 4retinal degeneration

Identifiers

PMID35563009
PMCPMC9103912
OpenAlexW4224280166

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.