Evidence map›Paper›PMID 35563125›Full record

ArticleInternational journal of molecular sciences2022

Pilot Study on Acute Effects of Pharmacological Intraperitoneal L-Homoarginine on Homeostasis of Lysine and Other Amino Acids in a Rat Model of Isoprenaline-Induced Takotsubo Cardiomyopathy.

Dimitrios Tsikas, Björn Redfors

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Amino Acids in Health and Disease: The Good, the Bad, and the Ugly.International journal of molecular sciences · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Dimitrios TsikasInstitute of Toxicology, Core Unit Proteomics, Hannover Medical School, 30623 Hannover, Germany.ORCID 0000-0001-6320-0956
Björn RedforsDepartment of Cardiology, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden.
Medizinische Hochschule Hannover · DESahlgrenska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-Arginine:glycine amidinotransferase (AGAT) catalyzes the formation of L-homoarginine (hArg) and L-ornithine (Orn) from L-arginine (Arg) and L-lysine (Lys): Arg + Lys ↔ hArg + Orn; equilibrium constant

Indexed as

HomoarginineTakotsubo CardiomyopathyAmino AcidsAnimalsArginineHomeostasisIsoproterenolLysinePilot ProjectsPutrescineRatsSpermidineAmino AcidsArginineHomoarginineIsoproterenolLysinePutrescineSpermidineAGATamino acidsGC-MSisoprenalineL-arginineL-homoarginineL-lysinepolyaminesputrescinesarcosinespermidine

Identifiers

PMID35563125
PMCPMC9103764
OpenAlexW4224866907

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.