Evidence map›Paper›PMID 35563541›Full record

ReviewInternational journal of molecular sciences2022

Nutritional Management of Thyroiditis of Hashimoto.

Yana Danailova, Tsvetelina Velikova, Georgi Nikolaev, Zorka Mitova, Alexander Shinkov, Hristo Gagov, Rossitza Konakchieva

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07048821 (The Impact of Mediterranean Diet on Patients With Hashimoto Thyroiditis), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07048821 nacompletednot on this mapstarted 2023, after this paper: background citation

The Impact of Mediterranean Diet on Patients With Hashimoto Thyroiditis

TypeinterventionalSponsorSherihan AboElyazed Mohamed KhalilRan2023 to 2023Enrolled40ConditionsHashimoto Thyroiditis, Mediterranean DietArmsDietary modification
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.

  1. Pooled it
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  15. Nutrition and Micronutrient Interactions in Autoimmune Thyroid Disorders: Implications for Cardiovascular Health.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Review
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yana DanailovaDepartment of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.
Tsvetelina VelikovaDepartment of Clinical Immunology, University Hospital Lozenetsz, Sofia University St. Kliement Ohridski, 1 "Kozyak" St., 1407 Sofia, Bulgaria.ORCID 0000-0002-0593-1272
Georgi NikolaevDepartment of Cell and Developmental Biology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.ORCID 0000-0003-0584-415X
Zorka MitovaInstitute of Experimental Morphology, Pathology and Anthropology with Museum, Bulgarian Academy of Sciences, Acad. G. Bonchev St., Blvd. 25, 1113 Sofia, Bulgaria.
Alexander ShinkovDepartment of Endocrinology, Medical Faculty, Medical University of Sofia, 2 Zdrave St., 1431 Sofia, Bulgaria.ORCID 0000-0002-9203-4149
Hristo GagovDepartment of Animal and Human Physiology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.ORCID 0000-0002-2759-7981
Rossitza KonakchievaDepartment of Cell and Developmental Biology, Faculty of Biology, Sofia University "St. Kliment Ohridski", 8 Dragan Tsankov Blvd., 1164 Sofia, Bulgaria.ORCID 0000-0001-7981-4506
Sofia University "St. Kliment Ohridski" · BGBulgarian Academy of Sciences · BGLozenetz Hospital · BGMedical University of Sofia · BG

Funding

H2020 INFRADEV-3-2019 871096 "EATRIS-Plus"Scientific Research Fund of the Ministry of Education and Science of Bulgaria KP-06-OPR03/18
6 · The paper itself

Abstract

Since the thyroid gland is one of the organs most affected by autoimmune processes, many patients with thyroiditis of Hashimoto (TH) seek medical advice on lifestyle variance and dietary modifications to improve and maintain their hyroid function. In this review, we aim to present and discuss some challenges associated with the nutritional management of TH, focusing on environmental and dietary deficits, inflammatory and toxic nutrients, cyanotoxins, etc. We discuss the relationships among different diets, chronic inflammation, and microbiota, and their impact on the development and exacerbation of TH in detail. We share some novel insights into the role of vitamin D and melatonin for preserving thyroid function during chronic inflammation in autoimmune predisposed subjects. A comprehensive overview is provided on anti-inflammatory nutrients and ecological diets, including foods for cleansing and detoxification, which represent strategies to prevent relapses and achieve overall improvement of life quality. In conclusion, data from biomedical and clinical studies provide evidence that an appropriate dietary and lighting regimen could significantly improve the function of the thyroid gland and reduce the reactivity of autoantibodies in TH. Compliance with nutritional guidelines may help TH patients to reduce the need for medicines.

Indexed as

Hashimoto DiseaseThyroiditisAutoantibodiesHumansInflammationAutoantibodiesanti-inflammatory nutrientsautoimmune Hashimoto’s thyroiditisdetoxificationecological dietproinflammatory

Identifiers

PMID35563541
PMCPMC9101513
OpenAlexW4229031090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.