Evidence map›Paper›PMID 35565636›Full record

ReviewAnimals : an open access journal from MDPI2022

Alternative Proteins for Fish Diets: Implications beyond Growth.

Cláudia Aragão, Ana Teresa Gonçalves, Benjamín Costas, Rita Azeredo, Maria João Xavier, Sofia Engrola

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
38.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 193 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Hemp Meal (Animals : an open access journal from MDPI · 2026
    Article
  8. Article
  9. Gut Microbiota Response in Meagre (Animals : an open access journal from MDPI · 2026
    Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Combined Dietary Effects ofAquaculture nutrition · 2026
    Article
  17. Review
  18. Review
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Cláudia AragãoCentre of Marine Sciences (CCMAR), Universidade do Algarve, 8005-139 Faro, Portugal.ORCID 0000-0002-9217-0183
Ana Teresa GonçalvesGreenCoLab-Associação Oceano Verde, Universidade do Algarve, 8005-139 Faro, Portugal.
Benjamín CostasInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), 4450-208 Matosinhos, Portugal.ORCID 0000-0003-3758-0849
Rita AzeredoInterdisciplinary Centre of Marine and Environmental Research (CIIMAR), 4450-208 Matosinhos, Portugal.ORCID 0000-0003-2486-595X
Maria João XavierCentre of Marine Sciences (CCMAR), Universidade do Algarve, 8005-139 Faro, Portugal.ORCID 0000-0003-4353-9586
Sofia EngrolaCentre of Marine Sciences (CCMAR), Universidade do Algarve, 8005-139 Faro, Portugal.ORCID 0000-0002-5244-5541
University of Algarve · PTCentro Interdisciplinar de Investigação Marinha e AmbientalSparos (Portugal) · PTUniversidade do Porto · PT

Funding

Fundação para a Ciência e Tecnologia UIDB/04326/2020; UIDP/04326/2020; LA/P/0101/2020; DL57/2016/CP1361/CT0033; 2020.00290.CEECIND
6 · The paper itself

Abstract

Aquaculture has been challenged to find alternative ingredients to develop innovative feed formulations that foster a sustainable future growth. Given the most recent trends in fish feed formulation on the use of alternative protein sources to decrease the dependency of fishmeal, it is fundamental to evaluate the implications of this new paradigm for fish health and welfare. This work intends to comprehensively review the impacts of alternative and novel dietary protein sources on fish gut microbiota and health, stress and immune responses, disease resistance, and antioxidant capacity. The research results indicate that alternative protein sources, such as terrestrial plant proteins, rendered animal by-products, insect meals, micro- and macroalgae, and single cell proteins (e.g., yeasts), may negatively impact gut microbiota and health, thus affecting immune and stress responses. Nevertheless, some of the novel protein sources, such as insects and algae meals, have functional properties and may exert an immunostimulatory activity. Further research on the effects of novel protein sources, beyond growth, is clearly needed. The information gathered here is of utmost importance, in order to develop innovative diets that guarantee the production of healthy fish with high quality standards and optimised welfare conditions, thus contributing to a sustainable growth of the aquaculture industry.

Indexed as

alternative protein sourcesaquaculturedisease resistancefish diet formulationsfishmeal replacementimmune responseintestinal healthmicrobiotaoxidative stressstress response

Identifiers

PMID35565636
PMCPMC9103129
OpenAlexW4229336593

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.