Evidence map›Paper›PMID 35565682›Full record

ReviewNutrients2022

The Role of Magnesium in the Pathogenesis of Metabolic Disorders.

Marta Pelczyńska, Małgorzata Moszak, Paweł Bogdański

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07265115 (Advanced Preventive Nutritional Supplements Targeting Pathologies in the Preclinical Phase), which is not on this map. Cited by 75 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 3 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07265115 nacompletednot on this mapstarted 2026, after this paper: background citation

Advanced Preventive Nutritional Supplements Targeting Pathologies in the Preclinical Phase

TypeinterventionalSponsorCentro de Edafología y Biología Aplicada del SeguraRan2026 to 2026Enrolled21ConditionsPrediabetesArmsPlacebo, Capsules with active ingredients, Placebo Repetition, Capsules with active ingredients Repetition
3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 3 syntheses or guidelines pooled it, 117 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Magnesium: Hype and Health Benefits.Current nutrition reports · 2026
    Review
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Marta PelczyńskaDepartment of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznań University of Medical Sciences, 84 Szamarzewskiego Street, 60-569 Poznań, Poland.ORCID 0000-0003-4548-032X
Małgorzata MoszakDepartment of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznań University of Medical Sciences, 84 Szamarzewskiego Street, 60-569 Poznań, Poland.ORCID 0000-0002-8965-6123
Paweł BogdańskiDepartment of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznań University of Medical Sciences, 84 Szamarzewskiego Street, 60-569 Poznań, Poland.ORCID 0000-0002-0563-1624
Poznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnesium (Mg) is an essential nutrient for maintaining vital physiological functions. It is involved in many fundamental processes, and Mg deficiency is often correlated with negative health outcomes. On the one hand, most western civilizations consume less than the recommended daily allowance of Mg. On the other hand, a growing body of evidence has indicated that chronic hypomagnesemia may be implicated in the pathogenesis of various metabolic disorders such as overweight and obesity, insulin resistance (IR) and type 2 diabetes mellitus (T2DM), hypertension (HTN), changes in lipid metabolism, and low-grade inflammation. High Mg intake with diet and/or supplementation seems to prevent chronic metabolic complications. The protective action of Mg may include limiting the adipose tissue accumulation, improving glucose and insulin metabolism, enhancing endothelium-dependent vasodilation, normalizing lipid profile, and attenuating inflammatory processes. Thus, it currently seems that Mg plays an important role in developing metabolic disorders associated with obesity, although more randomized controlled trials (RCTs) evaluating Mg supplementation strategies are needed. This work represents a review and synthesis of recent data on the role of Mg in the pathogenesis of metabolic disorders.

Indexed as

Diabetes Mellitus, Type 2Insulin ResistanceMagnesium DeficiencyHumansMagnesiumObesityMagnesiumbody weightdeficiencydiabetesdyslipidemiahypertensioninflammationmagnesiummetabolic syndromeobesity

Identifiers

PMID35565682
PMCPMC9103223
OpenAlexW4224240638

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.