Evidence map›Paper›PMID 35565885›Full record

ReviewNutrients2022

Personalized Nutrition in the Management of Female Infertility: New Insights on Chronic Low-Grade Inflammation.

Gemma Fabozzi, Giulia Verdone, Mariachiara Allori, Danilo Cimadomo, Carla Tatone, Liborio Stuppia, Marica Franzago, Nicolò Ubaldi, Alberto Vaiarelli, Filippo Maria Ubaldi and 2 more

Abstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Gemma FabozziB-Woman, 00197 Rome, Italy.
Giulia VerdoneB-Woman, 00197 Rome, Italy.
Mariachiara AlloriB-Woman, 00197 Rome, Italy.
Danilo CimadomoClinica Valle Giulia, GeneraLife IVF, 00197 Rome, Italy.
Carla TatoneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0002-4978-2571
Liborio StuppiaCenter for Advanced Studies and Technology (CAST), University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
Marica FranzagoCenter for Advanced Studies and Technology (CAST), University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-4830-8034
Nicolò UbaldiRadiology Unit, Department of Medical Surgical Sciences and Translational Medicine, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy.
Alberto VaiarelliClinica Valle Giulia, GeneraLife IVF, 00197 Rome, Italy.
Filippo Maria UbaldiClinica Valle Giulia, GeneraLife IVF, 00197 Rome, Italy.
Laura RienziClinica Valle Giulia, GeneraLife IVF, 00197 Rome, Italy.
Gianluca GennarelliLivet, GeneraLife IVF, 10126 Turin, Italy.ORCID 0000-0003-4390-9428

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing evidence on the significance of nutrition in reproduction is emerging from both animal and human studies, suggesting a mutual association between nutrition and female fertility. Different "fertile" dietary patterns have been studied; however, in humans, conflicting results or weak correlations are often reported, probably because of the individual variations in genome, proteome, metabolome, and microbiome and the extent of exposure to different environmental conditions. In this scenario, "precision nutrition", namely personalized dietary patterns based on deep phenotyping and on metabolomics, microbiome, and nutrigenetics of each case, might be more efficient for infertile patients than applying a generic nutritional approach. In this review, we report on new insights into the nutritional management of infertile patients, discussing the main nutrigenetic, nutrigenomic, and microbiomic aspects that should be investigated to achieve effective personalized nutritional interventions. Specifically, we will focus on the management of low-grade chronic inflammation, which is associated with several infertility-related diseases.

Indexed as

Infertility, FemaleAnimalsFemaleHumansInflammationMetabolomicsNutrigenomicsNutritional Statuschronic low-grade inflammationepigeneticsinfertilitymicrobiotanutrigeneticnutrigenomicsprecision nutrition

Identifiers

PMID35565885
PMCPMC9105997

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.