ArticleNutrients2022
Usual Intake of Flavonoids Is Inversely Associated with Metabolic Syndrome in African American and White Males but Not Females in Baltimore City, Maryland, USA.
Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The association of dietary polyphenols with obesity: a systematic review and meta-analysis.BMC endocrine disorders · 2026Pooled it
- Dietary polyphenols and the risk of metabolic syndrome: a systematic review and meta-analysis.BMC endocrine disorders · 2024Pooled it
- Inverse associations between dietary flavonoid and subclass intakes and frailty in U.S. adults.Frontiers in nutrition · 2025Article
- Dietary flavonoids may improve insulin resistance: NHANES, network pharmacological analyses and in vitro experiments.PloS one · 2025Article
- The association between dietary flavonoid intake and bone mineral density and osteoporosis in US adults: data from NHANES 2007-2008, 2009-2010 and 2017-2018.BMC public health · 2024Article
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- Dietary flavonoids intake contributes to delay biological aging process: analysis from NHANES dataset.Journal of translational medicine · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Despite research that suggests flavonoids protect against metabolic syndrome (MetS) and evidence that intake of these compounds differs by race, knowledge about whether flavonoid-MetS associations vary among racial groups is limited. This study sought to estimate usual total flavonoid intake in African American and White adults and assess its sex- and sex/race-specific associations with MetS and its risk factors. Analysis of cross-sectional data from 1837 adults participating in the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study were analyzed. Usual total flavonoid intake was estimated using the NCI Method, and logistic regression measured its linkages with health outcomes. Among males overall and when stratified by race, odds of MetS and its risk factors low high-density lipoprotein cholesterol (HDL-C) and elevated glucose were lower at the 75th percentile of usual total flavonoid intake than at the 25th percentile (OR for MetS = 0.62; 95% CI = 0.53, 0.71). However, low HDL-C and elevated glucose were positively associated with usual flavonoid intake among females. The comparable associations by race within sex imply that the relationships between flavonoid and health outcomes may be evident across an array of intakes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.