Evidence map›Paper›PMID 35566251›Full record

ReviewMolecules (Basel, Switzerland)2022

Hydrogels: Properties and Applications in Biomedicine.

Tzu-Chuan Ho, Chin-Chuan Chang, Hung-Pin Chan, Tze-Wen Chung, Chih-Wen Shu, Kuo-Pin Chuang, Tsai-Hui Duh, Ming-Hui Yang, Yu-Chang Tyan

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 412 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
412citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

412 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Article
  4. Designing PEDOT:PSS hydrogels for bioelectronic interfaces.Materials today (Kidlington, England) · 2026
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352 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tzu-Chuan HoDepartment of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chin-Chuan ChangDepartment of Nuclear Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
Hung-Pin ChanDepartment of Nuclear Medicine, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.ORCID 0000-0001-9741-5824
Tze-Wen ChungBiomedical Engineering Research and Development Center, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0002-7469-9913
Chih-Wen ShuDepartment of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Kuo-Pin ChuangGraduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, Pingtung 912, Taiwan.ORCID 0000-0002-3973-8390
Tsai-Hui DuhDepartment of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Ming-Hui YangDepartment of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.ORCID 0000-0001-5856-0498
Yu-Chang TyanDepartment of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0002-1917-5893

Funding

Ministry of Science and Technology MOST 109-2221-E-037-001-MY3
6 · The paper itself

Abstract

Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures, which can absorb relatively large amounts of fluid. Because of the high water content, soft structure, and porosity of hydrogels, they closely resemble living tissues. Research in recent years shows that hydrogels have been applied in various fields, such as agriculture, biomaterials, the food industry, drug delivery, tissue engineering, and regenerative medicine. Along with the underlying technology improvements of hydrogel development, hydrogels can be expected to be applied in more fields. Although not all hydrogels have good biodegradability and biocompatibility, such as synthetic hydrogels (polyvinyl alcohol, polyacrylamide, polyethylene glycol hydrogels, etc.), their biodegradability and biocompatibility can be adjusted by modification of their functional group or incorporation of natural polymers. Hence, scientists are still interested in the biomedical applications of hydrogels due to their creative adjustability for different uses. In this review, we first introduce the basic information of hydrogels, such as structure, classification, and synthesis. Then, we further describe the recent applications of hydrogels in 3D cell cultures, drug delivery, wound dressing, and tissue engineering.

Indexed as

HydrogelsTissue EngineeringBiocompatible MaterialsDrug Delivery SystemsPolymersBiocompatible MaterialsHydrogelsPolymers3D cell culturedrug deliveryhydrogelmedical applicationtissue engineeringwound dressing

Identifiers

PMID35566251
PMCPMC9104731

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.