Evidence mapPaperPMID 35566739Full record

ArticleJournal of clinical medicine2022

Utilization of Drug-Coated Balloons for the Treatment of Coronary Lesions in the Elderly Population.

Gal Sella, Gera Gandelman, Ortal Tuvali, Igor Volodarsky, Valeri Cuciuc, Dan Haberman, Omar Ayyad, Lion Poles, Michael Welt, Oscar Horacio Kracoff and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Application of Drug-Coated Balloons in Complex High Risk and Indicated Percutaneous Coronary Interventions.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Gal SellaThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Gera GandelmanThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Ortal TuvaliThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Igor VolodarskyThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Valeri CuciucThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Dan HabermanThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Omar AyyadThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Lion PolesThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Michael WeltThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Oscar Horacio KracoffThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Jacob GeorgeThe Heart Center, Kaplan Medical Center, The Hebrew University of Jerusalem, 1 Pasternak St., Rehovot 7661041, Israel.
Kaplan Medical Center · ILHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The use of drug-coated balloons (DCBs) has become more prevalent in the past few years for the treatment of in-stent restenosis (ISR) and de novo lesions. The absence of foreign polymer implantations potentially shortens the duration of dual anti-platelet therapy (DAPT), which can be beneficial for the elderly population. We aimed to investigate the safety and efficacy of the use of DCBs for the treatment of coronary lesions in elderly patients as compared to the younger population. Materials and methods: A database of 446 consecutive patients who underwent a procedure of DCB inflation in our institution was divided into two groups, below 70 years old and above 80 years old. We compared and analyzed the endpoints of total major adverse cardiovascular events (MACE), cardiovascular (CV) death, and all-cause mortality in both groups. Results: The difference in MACE between the two age groups was non-significant (p = 0.225); the difference in cardiovascular death was also non-significant (p = 0.086). All-cause mortality was significantly different (p < 0.0001) and can be attributed to the age of the patients. Conclusion: The utilization of DCBs for the treatment of coronary lesions may be as safe and effective for the elderly population as for the younger population and may allow a shorter period of DAPT therapy, which can lower the risk of bleeding.

Indexed as

atherosclerosisDCBgeriatricsre-stenosisrevascularizationTLR

Identifiers

PMID35566739
PMCPMC9099474
OpenAlexW4229020885

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.