ArticleJournal of orthopaedic surgery and research2022
Association between obesity and bone mineral density in middle-aged adults.
Article in Journal of orthopaedic surgery and research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 58 citations in OpenAlex.
- A Large-Scale Multi-omics Polygenic Risk Score Analysis Identified Candidate Biomarkers Associated with Heel Bone Mineral Density.Calcified tissue international · 2026Article
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- Association between conicity index and osteoporosis/femoral bone mineral density in USA adults : a cross-sectional study based on evidence from the National Health and Nutrition Examination Survey (2005 to 2020).Bone & joint research · 2026Article
- Association of triglyceride glucose index and volumetric bone mineral density in T2DM: fat distribution as a potential indirect link.Frontiers in cell and developmental biology · 2026Article
- An explainable predictive machine learning model of osteopenia for perimenopausal women based on clinical data: a retrospective single-center study.Frontiers in endocrinology · 2026Article
- Cellular mechanisms of osteoporosis: A comprehensive perspective on ferroptosis, cuproptosis and lipid metabolism abnormalities.Biomaterials translational · 2026Review
- Increased inflammation burden index increasing the risk of poor prognosis in patients with chronic kidney disease in NHANES study.Renal failure · 2025Article
- Radiation Decreases Bone Density while Diabetes Increases Osteoarthritis in Non-Human Primates.Radiation research · 2025Article
- Assessing the impact of metabolic syndrome on the accuracy of vertebral bone quality in determining bone mineral density in patients undergoing lumbar fusion surgery.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Prevalence of Impaired Bone Health in Premature Ovarian Insufficiency and Early Menopause and the Impact of Time to Diagnosis.Journal of clinical medicine · 2025Article
- The association between lipid accumulation products and bone mineral density in U.S. Adults, a nationally representative cross-sectional study.Scientific reports · 2025Article
- Weight-adjusted waist index as a new predictor of osteoporosis in postmenopausal patients with T2DM.Scientific reports · 2025Article
- Associations between abdominal fat, psoas muscle fat, and lumbar spine bone density: insights from quantitative CT imaging.BMC musculoskeletal disorders · 2025Article
- Association between a body shape index and bone mineral density in US adults based on NHANES data.Scientific reports · 2025Article
- Negative correlation between relative fat mass and bone mineral density: NHANES 2011-2018.Frontiers in public health · 2025Article
- Weight-adjusted waist index associated with bone mineral density in rheumatoid arthritis patients: a cross-sectional study.Clinical rheumatology · 2025Article
- Editorial: Advances in the pathogenesis and treatment of osteoporosis: from bench to bedside.Frontiers in medicine · 2025Article
- Association between cardiometabolic index and bone mineral density among adolescents in the United States.Frontiers in endocrinology · 2025Article
- Exploring the impact of body mass index on the accuracy of vertebral bone quality in determining bone mineral density in patients undergoing lumbar fusion surgery.Journal of orthopaedic surgery and research · 2024Article
- Gastrointestinal health and serum proteins are associated with BMD in postmenopausal women: a cross-sectional study.Nutrition & metabolism · 2024Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
backgroundThe relationship between obesity and bone mineral density (BMD) varies in different studies. Our aim in this study was to explore the association between obesity (body mass index ≥ 30) and BMD among adults 40-59 years of age.
methodsThis study was conducted on a sample of 2218 participants (986 men and 1232 women) aged 40 to 59 years from the National Health and Nutrition Examination Survey 2011-2018. The independent variable was body mass index (BMI). The outcome variable was lumbar BMD. The associations of BMI with lumbar BMD were examined using multivariable linear regression models.
resultsBMI was positively associated with lumbar BMD after adjusting for other covariates [β 0.006; 95% confidence interval (CI) 0.003-0.008]. An inverted U-shaped association between BMI and lumbar BMD was further identified, with the point of infection at approximately 50 kg/m
conclusionBased on the results, it may be beneficial to appropriately increase BMI to promote BMD. However, considering the inverted U-shaped association, excessive BMI may be harmful to bone health in women and blacks.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.