Evidence map›Paper›PMID 35577351›Full record

ArticleBioengineered2022

Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer.

Weilu Wu, Shijie Zhou, Tianmin Liu, Dongni Liang

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Subcellular Stress Markers in Epithelial Ovarian Cancer.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Mitochondria transcription and cancer.Cell death discovery · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Weilu WuDepartment of Pathology, West China Second University Hospital, Sichuan University, Chengdu, China.
Shijie ZhouState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Tianmin LiuDepartment of Pathology, West China Second University Hospital, Sichuan University, Chengdu, China.
Dongni LiangDepartment of Pathology, West China Second University Hospital, Sichuan University, Chengdu, China.
West China Second University Hospital of Sichuan University · CNState Key Laboratory of Biotherapy

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial transcription factor B2 (TFB2M) is a protein modulating both mitochondrial DNA (mtDNA) transcription and compacting. In this study, we explored the expression profile of

Indexed as

DNA, MitochondrialInterleukin-6MacrophagesMethyltransferasesMitochondrial ProteinsOvarian NeoplasmsTranscription FactorsCarcinoma, Ovarian EpithelialCell Line, TumorDeoxyribonuclease IFemaleHumansMitochondriaNF-kappa BToll-Like Receptor 9Tumor MicroenvironmentDeoxyribonuclease IDNA, MitochondrialInterleukin-6MethyltransferasesMitochondrial ProteinsNF-kappa BTFB2M protein, humanToll-Like Receptor 9Transcription FactorsIL-6mtDNAovarian cancerTBF2MTLR9

Identifiers

PMID35577351
PMCPMC9275939
OpenAlexW4280504036

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.