SynthesisThe American journal of medicine2022
Alcohol Consumption and Cardiovascular Health.
Synthesis in The American journal of medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Evolving Research Focus on Diet and Cardiovascular Disease: A Systematic Review of 298 Cohort Studies Published from 2019 to 2024.Nutrients · 2025Pooled it
- Lifestyle behaviours do not moderate the association between childhood maltreatment and comorbid depression and cardiometabolic disease in older adults: a meta-analysis.BMC medicine · 2025Pooled it
- Predictive value of remnant cholesterol for in-stent restenosis after drug-eluting stent implantation.Medicine · 2026Article
- Identifying drinking patterns in a middle-aged population and their association with coronary heart disease, stroke, and all-cause mortality risk: the Danish Health Examination Survey.European journal of public health · 2026Article
- Article
- Subtype Differences in Major Adverse Liver Outcomes and Cardiovascular Events and Mortality in Steatotic Liver Disease: A UK Biobank Analysis.Alimentary pharmacology & therapeutics · 2026Article
- Cardiac organoids in toxicology: from construction strategies and research trends to precision screening applications.Stem cell research & therapy · 2026Review
- Impact of Moderate Wine Consumption on Type 2 Diabetes.Nutrients · 2026Review
- Contribution of Sport Type to the Association Between Handgrip Strength and Morbidity/Mortality: Future Follow-up Study and Possible Mechanisms.Sports medicine - open · 2026Review
- Inhibitory effects of ethanol on pathological high shear stress-induced platelet adhesion and aggregation: a microfluidic chip model study.Thrombosis journal · 2026Article
- A Comprehensive Analysis of the Impact of Nutrient Intakes on the Stages and Mortality of Cardiovascular-Kidney-Metabolic Syndrome.Food science & nutrition · 2026Article
- Relationships of patient risk profiles and receipt of specialty treatment with early, sustained, and stable cessation of heavy alcohol use across populations.Journal of substance use and addiction treatment · 2026Article
- Risk of substance-related problems in hypochondriasis.Psychological medicine · 2026Article
- Chronic alcohol consumption on retinal microcirculation in healthy subjects: an optic coherence tomography angiography study.International journal of ophthalmology · 2026Article
- First-year emotional health after liver transplantation: a prospective cohort study.Frontiers in psychology · 2026Article
- Article
- 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Alcohol Consumption and Acute Coronary Syndrome: Epidemiology, Pathophysiology, and Clinical Perspectives.Journal of clinical medicine · 2025Review
- Higher adherence to (poly)phenol-rich diet is associated with lower CVD risk in the TwinsUK cohort.BMC medicine · 2025Article
- Screening Beyond Dependence: At-Risk Drinking and Psychosocial Correlates in the Heart Transplant Population.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 9 institutions in 2 countries.
Funding
Abstract
backgroundStudies evaluating alcohol consumption and cardiovascular diseases have shown inconsistent results.
methodsWe performed a systematic review of peer-reviewed publications from an extensive query of Ovid MEDLINE, Ovid Embase, Ovid Cochrane Database of Systematic Reviews, Scopus, and Web of Science from database inception to March 2022 for all studies that reported the association between alcohol consumption in terms of quantity (daily or weekly amounts) and type of beverage (wine, beer or spirit) and cardiovascular disease events.
resultsThe study population included a total of 1,579,435 individuals based on 56 cohorts from several countries. We found that moderate wine consumption defined as 1-4 drinks per week was associated with a reduction in risk for cardiovascular mortality when compared with beer or spirits. However, higher risk for cardiovascular disease mortality was typically seen with heavier daily or weekly alcohol consumption across all types of beverages.
conclusionsIt is possible that the observational studies may overestimate the benefits of alcohol for cardiovascular disease outcomes. Although moderate wine consumption is probably associated with low cardiovascular disease events, there are many confounding factors, in particular, lifestyle, genetic, and socioeconomic associations with wine drinking, which likely explain much of the association with wine and reduced cardiovascular disease events. Further prospective study of alcohol and all-cause mortality, including cancer, is needed.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.