Evidence map›Paper›PMID 35585376›Full record

ReviewMolecular biology reports2022

Krüppel-like factors in glycolipid metabolic diseases.

Yutong Li, Xiaotong Zhao, Murong Xu, Mingwei Chen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. C(P)XCG Proteins ofInternational journal of molecular sciences · 2024
    Article
  10. Review
  11. Genome-Wide Analysis of theAnimals : an open access journal from MDPI · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yutong LiDepartment of Endocrinology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, 230032, Hefei, Anhui, China.
Xiaotong ZhaoDepartment of Endocrinology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, 230032, Hefei, Anhui, China.
Murong XuDepartment of Endocrinology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, 230032, Hefei, Anhui, China.
Mingwei ChenDepartment of Endocrinology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, 230032, Hefei, Anhui, China. chmw1@163.com.ORCID http://orcid.org/0000-0002-8439-0469
Anhui Medical University · CN

Funding

Natural Science Foundation of Anhui Province 2108085MH269
6 · The paper itself

Abstract

Krüppel-like factors (KLFs) are a family of transcription factors characterised by zinc-finger structures at the C-terminal. They play the key roles in cell proliferation, differentiation, and migration, as well as in embryonic development. They have been widely expressed in multiple systems in vivo, and their dysregulation is closely associated with a variety of human diseases. Glycolipid metabolism is a complex physiological process which can be regulated at the transcriptional level. Glycolipid metabolic diseases, such as obesity, non-alcoholic fatty liver disease, diabetes, and their complications, are a serious threat to human health. Recently, increasing studies have shown that KLFs are closely related to glycolipid metabolism and energy balance of the liver, adipose tissue, heart, skeletal muscle, lung, pancreas, and nervous system. In this review, we focused on the correlation between the subtypes of the KLF family and glycolipid metabolic diseases to describe new directions and trends in endocrine and glycolipid metabolic disease treatments.

Indexed as

Kruppel-Like Transcription FactorsMetabolic DiseasesAdipose TissueGlycolipidsHumansZinc FingersGlycolipidsKruppel-Like Transcription FactorsGlycolipid metabolic diseaseKLFsResearch progressTranscription factors

Identifiers

PMID35585376
OpenAlexW4280562370

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.