Evidence map›Paper›PMID 35590129›Full record

ArticleMed (New York, N.Y.)2021

An Organ-on-a-Chip System to Study Anaerobic Bacteria in Intestinal Health and Disease.

Locke Davenport Huyer, Milica Radisic

Abstract readComment
PubMed Publisher
In one paragraph

Article in Med (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Locke Davenport HuyerDepartment of Chemical Engineering and Applied Chemistry, Institute of Biomedical Engineering University of Toronto, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada.
Milica RadisicDepartment of Chemical Engineering and Applied Chemistry, Institute of Biomedical Engineering University of Toronto, Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada. Electronic address: m.radisic@utoronto.ca.
University Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A state-of-the-art organ-on-a-chip system enabled co-culture of highly oxygen-sensitive Faecalibacterium prausnitzii with human intestinal epithelial cells, recapitulating a critical role of the bacteria in the maintenance of anti-inflammatory phenotype of gut epithelium mediated by bacteria-secreted butyrate.

Indexed as

Bacteria, AnaerobicIntestinal MucosaFaecalibacterium prausnitziiIntestinesLab-On-A-Chip Devices

Identifiers

PMID35590129
OpenAlexW3119684277

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.