Evidence map›Paper›PMID 35591817›Full record

ArticleArchives of medical science : AMS2022

Design and rationale of a nationwide screening analysis from the LIPIDOGRAM2015 and LIPIDOGEN2015 studies.

Jacek J Jóźwiak, Sławomir Kasperczyk, Tomasz Tomasik, Tadeusz Osadnik, Adam Windak, Krzysztof Studziński, Mirosław Mastej, Alberico Catapano, Kausik K Ray, Dimitri P Mikhailidis and 16 more

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Antioxidant System and Ions Concentrations After Femoral Neck and Resurfacing Hip Arthroplasty.Medical science monitor : international medical journal of experimental and clinical research · 2022
    Article
  12. Observational
  13. An insertion mutation in theArchives of medical sciences. Atherosclerotic diseases · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Jacek J JóźwiakDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Opole, Opole, Poland.
Sławomir KasperczykDepartment of Biochemistry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Tomasz TomasikChair of Family Medicine, Jagiellonian University Medical College, Krakow, Poland.
Tadeusz OsadnikDepartment of Pharmacology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Adam WindakChair of Family Medicine, Jagiellonian University Medical College, Krakow, Poland.
Krzysztof StudzińskiChair of Family Medicine, Jagiellonian University Medical College, Krakow, Poland.
Mirosław MastejMastej Medical Centre, Jasło, Poland.
Alberico CatapanoDepartment of Pharmacological Sciences University of Milano and Multimedica IRCCS, Milano, Italy.
Kausik K RayImperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College, Kensington, London, UK.
Dimitri P MikhailidisDepartment of Clinical Biochemistry, Royal Free Hospital, University College London, London, UK.
Peter P TothCicarrone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland, and CGH Medical Center, Sterling, Illinois, USA.
George HowardDepartment of Biostatistics, School of Public Health of Alabama, Birmingham, AL, USA.
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom; and Aalborg Thrombosis Research Unit, Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Maciej TomaszewskiDivision of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Fadi J CharcharSchool of Health and Life Sciences, Federation University Australia, Ballarat, Victoria, Australia.
Naveed SattarInstitute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, UK.
Bryan WilliamsNIHR University College London Biomedical Research Centre, University College London and University College London Hospitals NHS Foundation Trust, London, UK.
Thomas M MacDonaldMEMO Research, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
Paweł KrzemieńEuroimmun Polska Sp. z o.o., Poland.
Michał DobrakowskiDepartment of Biochemistry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Aleksandra KasperczykDepartment of Biochemistry, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland.
Dariusz NowakMunicipal Hospital, Czestochowa, Poland.
Łukasz SkowronDepartment of Gastroenterology and Internal Diseases, Military Institute of Medicine, Warsaw, Poland.
Żaneta ŻakDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Opole, Opole, Poland.
Joanna LewekPolish Mothers Memorial Hospital Research Institute, Lodz, Poland.
Maciej BanachPolish Mothers Memorial Hospital Research Institute, Lodz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Cardiovascular disease (CVD) is a major cause of morbidity and mortality throughout the world. The LIPIDOGRAM2015 study was performed to estimate the prevalence of risk factors for atherosclerotic diseases as well as cardiovascular and related disorders in the primary care setting in Poland. The LIPIDOGEN2015 sub-study was designed to include a random cohort of patients in order to analyse parameters related to lipid metabolism, oxidative stress, inflammatory responses, autoimmune disorders, and gene variants that confer susceptibility to cardiometabolic and atherosclerotic diseases. Material and methods: The recruitment was carried out by 438 primary care physicians in Poland. The expected number of patients recruited for the LIPIDOGRAM2015 study was 13,000-14,000 with 13-15% (1700-2000) also participating in the LIPIDOGEN2015 sub-study. Each patient had to complete a questionnaire concerning medical and family history, concomitant diseases, and pharmacotherapy. Anthropometric measurements were performed at the doctor's office. For the LIPIDOGEN2015 sub-study, saliva samples for DNA isolation and blood samples for measurement of glycated haemoglobin, oxidative stress parameters, autoantibody levels, and inflammatory cytokine profile and apolipoprotein profile were collected. Follow-up data will be obtained from the National Health Fund in Poland. Results: The LIPIDOGRAM2015 and LIPIDOGEN2015 study cohort reflects the prevalence of cardiovascular risk factors and concomitant diseases, markers of oxidative stress, the presence of autoantibodies, inflammatory cytokine profile, and apolipoprotein profile, as well as genetic variants potentially conferring susceptibility to cardiometabolic and atherosclerotic diseases. Conclusions: This study presents the prevalence of different CV risk factors, with special emphasis on lipid disorders, and it assesses the relationship between inflammation, oxidative stress, and mutations in genes encoding proteins regulating lipid metabolism, as well as genes conferring susceptibility to cardiovascular, cardiometabolic, and related diseases.

Indexed as

atherosclerosiscardiometabolic diseasescardiovascular diseasesdyslipidaemiagenesinflammationoxidative stress

Identifiers

PMID35591817
PMCPMC9103403

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.