Evidence map›Paper›PMID 35591821›Full record

ArticleArchives of medical science : AMS2022

Is it time to change the goals of lipid management in type 1 diabetes mellitus? Changes in apolipoprotein levels during the first year of type 1 diabetes mellitus. Prospective InLipoDiab1 study.

Aleksandra Cieluch, Aleksandra Uruska, Marcin Nowicki, Ewa Wysocka, Paweł Niedźwiecki, Agata Grzelka-Woźniak, Justyna Flotyńska, Dorota Zozulińska-Ziółkiewicz

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aleksandra CieluchDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Aleksandra UruskaDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Marcin NowickiDepartment of Clinical Biochemistry and Laboratory Medicine, Poznan University of Medical Sciences, Poznan, Poland.
Ewa WysockaDepartment of Laboratory Diagnostics, Poznan University of Medical Sciences, Poznan, Poland.
Paweł NiedźwieckiDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Agata Grzelka-WoźniakDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Justyna FlotyńskaDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Dorota Zozulińska-ZiółkiewiczDepartment of Internal Medicine and Diabetology, Poznan University of Medical Sciences, Poznan, Poland.
Poznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Apolipoprotein complement is a critical determinant of lipoprotein function and metabolism. The relation between exogenous insulin and apolipoproteins (apos) in newly diagnosed type 1 diabetes mellitus (T1DM) has not yet been studied extensively. The aim of this study was to prospectively observe the changes in serum apos AI (apo AI) and AII (apo AII) in patients with newly diagnosed T1DM and their association with the daily insulin requirement. Material and methods: Thirty-four participants of the InLipoDiab1 study aged 26 (IQR: 22-32) were enrolled in this analysis. Apolipoprotein AI and AII concentrations were assessed at diagnosis and at follow-up after 3 weeks, 6 months, and 1 year of insulin treatment. The daily dose of insulin (DDI) was calculated as the amount of short- and long-acting insulin at discharge from the hospital and at follow-up visits. Results: The changes in apo AI concentration were observed after 3 weeks of insulin treatment ( Conclusions: In the first year of T1DM, there is a significant increase in apos concentration. Due to the significant deviation of apos concentration from accepted norms, changes in the recommendations of lipid control criteria in T1DM may be considered.

Indexed as

apolipoproteinsatherosclerosisHDL metabolisminsulin therapytype 1 diabetes mellitus

Identifiers

PMID35591821
PMCPMC9103612
OpenAlexW3097770956

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.