Evidence map›Paper›PMID 35594528›Full record

ArticleHuman vaccines & immunotherapeutics2022

Need of booster vaccine doses to counteract the emergence of SARS-CoV-2 variants in the context of the Omicron variant and increasing COVID-19 cases: An update.

Ranjan K Mohapatra, Nahed A El-Shall, Ruchi Tiwari, Firzan Nainu, Venkataramana Kandi, Ashish K Sarangi, Teroj Abdulrahman Mohammed, Perumal Arumugam Desingu, Chiranjib Chakraborty, Kuldeep Dhama

Open access · goldAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  4. Immunization against Medically Important Human Coronaviruses of Public Health Concern.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 4 countries.

Ranjan K MohapatraDepartment of Chemistry, Government College of Engineering, Keonjhar, India.ORCID 0000-0001-7623-3343
Nahed A El-ShallDepartment of Poultry and Fish Diseases, Faculty of Veterinary Medicine, Alexandria University, Edfina, El-Beheira, Egypt.ORCID 0000-0002-2013-487X
Ruchi TiwariDepartment of Veterinary Microbiology and Immunology, College of Veterinary Sciences, Uttar Pradesh Pandit DeenDayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go Anusandhan Sansthan (DUVASU), Mathura, India.ORCID 0000-0001-7763-5547
Firzan NainuDepartment of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia.
Venkataramana KandiDepartment of Microbiology, Prathima Institute of Medical Sciences, Karimnagar, India.
Ashish K SarangiDepartment of Chemistry, School of Applied Sciences, Centurion University of Technology and Management, Balangir, India.
Teroj Abdulrahman MohammedDental Basic Science Department, College of Dentistry, University of Duhok, Duhok, Iraq.ORCID 0000-0002-9538-9789
Perumal Arumugam DesinguDepartment of Microbiology and Cell Biology, Indian Institute of Science, Bengaluru, India.
Chiranjib ChakrabortyDepartment of Biotechnology, School of Life Science and Biotechnology, Adamas University, Kolkata, India.ORCID 0000-0002-3958-239X
Kuldeep DhamaDivision of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, India.ORCID 0000-0001-7469-4752
Adamas University · INAlexandria University · EGCenturion University of Technology and Management · INGovernment College of Engineering, Keonjhar · INHasanuddin University · IDIndian Institute of Science Bangalore · INIndian Veterinary Research Institute · INInstitute of Medical Sciences · INUniversity of Duhok · IQUttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of different variants of SARS-CoV-2, including the Omicron (B.1.1.529) variant in November 2021, has resulted in a continuous major health concern at a global scale. Presently, the Omicron variant has spread very rapidly worldwide within a short time period. As the most mutated variant of SARS-CoV-2, Omicron has instilled serious uncertainties on the effectiveness of humoral adaptive immunity generated by COVID-19 vaccination or an active viral infection as well as the protection provided by antibody-based immunotherapies. Amidst such high public health concerns, the need to carry out booster vaccination has been emphasized. Current evidence reveals the importance of incorporating booster vaccination using several vaccine platforms, such as viral vector- and mRNA-based vaccines, as well as other platforms that are under explorative investigations. Further research is being conducted to assess the effectiveness and durability of protection provided by booster COVID-19 vaccination against Omicron and other SARS-CoV-2 variants.

Indexed as

COVID-19Viral VaccinesCOVID-19 VaccinesHumansSARS-CoV-2COVID-19 VaccinesViral VaccinesB.1.1.529booster dosesenhancing immunityOmicron variantprotectionSARS-CoV-2vaccines

Identifiers

PMID35594528
PMCPMC9897647
OpenAlexW4281263168

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.