ArticleCardiovascular diabetology2022
Association of the atherogenic index of plasma with cardiovascular risk beyond the traditional risk factors: a nationwide population-based cohort study.
Article in Cardiovascular diabetology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
105 citing papers in PubMed, 4 syntheses or guidelines pooled it, 187 citations in OpenAlex.
- The association between triglyceride-glucose index and polycystic ovary syndrome: a systematic review and meta-analysis across different populations.Journal of ovarian research · 2025Pooled it
- Atherogenic index of plasma and coronary artery disease: a systematic review and meta-analysis of observational studies.Cardiovascular diabetology · 2025Pooled it
- Association between atherogenic index of plasma and depression risk: a meta-analysis.Frontiers in psychiatry · 2025Pooled it
- The association of atherogenic index of plasma with cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis.Cardiovascular diabetology · 2024Pooled it
- The effects of early short-term insulin treatment vs. glimepiride on beta cell function in newly diagnosed type 2 diabetes with HbA1c above 9.Turkish journal of medical sciences · 2023Trial
- Carotid Atherosclerosis and Metabolic Characteristics Among High-Risk Cardiovascular Populations of Four Ethnic Groups - Yunnan Province, China, 2024.China CDC weekly · 2026Article
- Cardiovascular Risk and Bone Mineral Density in Children with Familial Mediterranean Fever: The Role of Disease Severity and Genetic Mutations.International journal of molecular sciences · 2026Article
- The association of nontraditional lipid parameters with all-cause and cardiovascular mortality: A national cohort study.Medicine · 2026Article
- Article
- Joint association of atherogenic index of plasma and estimated glucose disposal rate with new-onset cardiovascular disease risk in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3: a 9-year nationwide prospective cohort study.Cardiovascular diabetology · 2026Article
- Remnant Cholesterol Inflammatory Index and Its Association With All-Cause Mortality Among General Population and Individuals With Cardiovascular-Kidney-Metabolic Syndrome Stages 0-3: Evidence From Two Nationwide Studies.Clinical cardiology · 2026Article
- Impact of a Hypocaloric Diet on Prognostic Biomarkers of Endothelial Dysfunction: A Prospective Study.Journal of clinical medicine · 2026Article
- Association between atherosclerotic index of plasma and long-term aortic-related adverse events in type B aortic dissection patients undergoing thoracic endovascular aortic repair.Cardiovascular diabetology · 2026Article
- Vitamin B12 Status and Cardiovascular Risk: Novel Insights from NMR-Based Lipoprotein Profiling in 20,665 Adults.Journal of clinical medicine · 2026Article
- Lipid-based atherogenic indices and their relationship with cardiovascular disease risk in an African population of type 2 diabetes mellitus patients.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Comparison of TyG indices and atherogenic index of plasma with hypertension in the PERSIAN Guilan cohort.Scientific reports · 2026Article
- Mediation by atherogenic index of plasma of the association between body roundness index and cognitive impairment in older Chinese people: an analysis using health check-up data.Frontiers in public health · 2026Article
- The Predictive Value of Atherogenic Index of Plasma for the Presence of Slow Coronary Flow Phenomenon in Patients with Chest Pain and No Obstructive Coronary Arteries: A Single-Center Retrospective Study.International journal of general medicine · 2026Article
- Predictive Factors of Low HDL-C in Patients with Schizophrenia.Neuropsychiatric disease and treatment · 2026Article
- Impacts of Herbal Medicine Use on Lipid Profiles in Type 2 Diabetic Patients in Northwest Ethiopia: A Comparative Cross-Sectional Study.BioMed research international · 2026Article
45 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe atherogenic index of plasma (AIP) is composed of triglycerides and high-density lipoprotein cholesterol and is a novel marker for assessing the risk of atherogenicity and cardiometabolic health. An association between AIP and greater frequency of major adverse cardiovascular events (MACEs) in patients with type 2 diabetes mellitus and high cardiovascular (CV) disease risk has been reported. However, only few studies have examined the correlation between AIP and CV risk in general populations. We thus aimed to evaluate the relationship between AIP and CV diseases using a large-scale population dataset from the Korean National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS).
methodsA total of 514,866 participants were enrolled from the NHIS-HEALS and classified according to the AIP quartiles. We performed univariate and multivariate Cox proportional hazards regression analyses to determine the association between AIP and MACEs, CV events, and CV mortality.
resultsDuring follow-up, we documented 12,133, 11,055, and 1942 cases of MACEs, CV events, and CV mortality, respectively. The multivariate-adjusted hazard ratios [HRs; 95% confidence interval (CI)] for MACEs gradually and significantly increased with the AIP quartiles [1.113 (1.054-1.175) in Q2, 1.175 (1.113-1.240) in Q3, and 1.278 (1.209-1.350) in Q4], following an adjustment for the conventional CV risk factors, including age, sex, body mass index, smoking, alcohol drinking, physical activities, household income, fasting glucose, systolic blood pressure, low-density lipoprotein cholesterol, and estimated glomerular filtration rate. In subgroup analyses, the association of AIP with MACEs and CV events was particularly outstanding in patients with diabetes.
conclusionsAIP was significantly associated with CV risks after adjusting for the traditional risk factors. Therefore, it may be used as an effective mass screening method to identify patients at a high risk of CV events.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.