Evidence mapPaperPMID 35599596Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2022

Temporal patterns, characteristics, and predictors of clinical outcomes in patients undergoing percutaneous coronary intervention for stent thrombosis.

Mohamed O Mohamed, Alex Sirker, Alaide Chieffo, Pablo Avanzas, James Nolan, Muhammad Rashid, Mohamed Dafaalla, Saadiq Moledina, Peter Ludman, Tim Kinnaird and 1 more

Open access · greenAbstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Mohamed O MohamedKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, United Kingdom.
Alex SirkerDepartment of Cardiology, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Alaide ChieffoDepartment of Cardiology, San Raffaele Hospital, Milan, Italy.
Pablo AvanzasDepartment of Cardiology, Hospital Universitario Central de Asturias, Oviedo, Spain.
James NolanDepartment of Cardiology, Royal Stoke University Hospital, Stoke-on-Trent, United Kingdom.
Muhammad RashidKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, United Kingdom.
Mohamed DafaallaKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, United Kingdom.
Saadiq MoledinaKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, United Kingdom.
Peter LudmanInstitute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom.
Tim KinnairdDepartment of Cardiology, University Hospital of Wales, Cardiff, United Kingdom.
Mamas A MamasKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, United Kingdom.
Royal Stoke University Hospital · GBKeele University · GBUniversity College London · GBHospital Universitario Central de Asturias · ESUniversity Hospital of Wales · GBUniversity of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are limited data on the outcomes of percutaneous coronary intervention (PCI) following stent thrombosis (ST) and differences exist based on timing.

aimsOur aim was to study the rates of PCI procedures for an ST indication among all patients admitted for PCI at a national level and to compare their characteristics and procedural outcomes based on ST timing.

methodsAll PCI procedures in England and Wales (2014-2020) were retrospectively analysed and stratified by the presence of ST into four groups: non-ST, early ST (0-30 days), late ST (>30-360 days), very late ST (>360 days). Multivariable logistic regression models were performed to assess the odds ratios (OR) of in-hospital MACCE (major adverse cardiovascular and cerebrovascular events, a composite of mortality, acute stroke and reinfarction) and mortality.

resultsOverall, 7,923 (1.4%) procedures were for ST indication, most commonly for early ST (n=4,171; 52.6%), followed by very late ST (n=2,801; 35.4%) and late ST (n=951; 12.0%). The rate of PCI for ST declined between 2014 and 2020 (1.7 to 1.4%; p<0.001). Early ST was the only subgroup associated with increased odds of MACCE (OR 1.22, 95% CI: 1.05-1.41), all-cause mortality (OR 1.21, 95% CI: 1.07-1.36) and reinfarction (OR 2.48, 95% CI: 1.48-4.14), compared with non-ST indication. The odds of mortality were significantly reduced in ST patients with the use of intravascular imaging (OR 0.66, 95% CI: 0.48-0.92) and newer P2Y

conclusionsPCI for ST has declined in frequency over a 7-year period, with most procedures performed for early ST. Among the different times of ST onset, only early ST is associated with worse clinical outcomes after PCI. Routine use of intravascular imaging and newer P2Y

Indexed as

Percutaneous Coronary InterventionThrombosisHumansPlatelet Aggregation InhibitorsPrasugrel HydrochlorideRetrospective StudiesStentsTicagrelorTreatment OutcomePlatelet Aggregation InhibitorsPrasugrel HydrochlorideTicagrelor

Identifiers

PMID35599596
PMCPMC10241267
OpenAlexW4282918052

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.