Evidence map›Paper›PMID 35600069›Full record

ArticleCureus2022

Gestational Intermittent Hypoxia Induces Mitochondrial Impairment in the Geniohyoid Muscle of Offspring Rats.

Wirongrong Wongkitikamjorn, Jun Hosomichi, Eiji Wada, Hideyuki Maeda, Sirichom Satrawaha, Haixin Hong, Yukiko K Hayashi, Ken-Ichi Yoshida, Takashi Ono

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Wirongrong WongkitikamjornDepartment of Orthodontic Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, JPN.
Jun HosomichiDepartment of Orthodontic Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, JPN.
Eiji WadaDepartment of Pathophysiology, Tokyo Medical University, Tokyo, JPN.
Hideyuki MaedaDepartment of Forensic Medicine, Tokyo Medical University, Tokyo, JPN.
Sirichom SatrawahaDepartment of Orthodontics, Faculty of Dentistry, Chulalongkorn University, Bangkok, THA.
Haixin HongDepartment of Orthodontic Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, JPN.
Yukiko K HayashiDepartment of Pathophysiology, Tokyo Medical University, Tokyo, JPN.
Ken-Ichi YoshidaDepartment of Forensic Medicine, Tokyo Medical University, Tokyo, JPN.
Takashi OnoDepartment of Orthodontic Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, JPN.
Tokyo Medical University · JPShenzhen University · CNChulalongkorn University · THTokyo Medical and Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Gestational intermittent hypoxia (IH), a hallmark of obstructive sleep apnea during gestation, alters respiratory neural control and diaphragm muscle contractile function in the offspring. The geniohyoid (GH) muscle is innervated by the respiratory-related hypoglossal nerve and plays a role in tongue traction and suckling, motor behaviors that then give way to chewing. Here, we aimed to investigate the effects of gestational exposure to IH on the muscle development and metabolism of GH and masseter muscles in male offspring rats. Materials and methods Pregnant Sprague-Dawley rats were exposed to IH (3-min periods of 4-21% O

Indexed as

geniohyoid muscleintermittent hypoxiamasseter musclesobstructive sleep apneaoffspring ratpregnancy

Identifiers

PMID35600069
PMCPMC9117862
OpenAlexW4280595568

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.