Evidence mapPaperPMID 35600992Full record

ArticleFrontiers in behavioral neuroscience2022

Pomegranate and Its Components, Punicalagin and Ellagic Acid, Promote Antidepressant, Antioxidant, and Free Radical-Scavenging Activity in Ovariectomized Rats.

Nancy Cervantes-Anaya, Gabriel Azpilcueta-Morales, Erika Estrada-Camarena, Daniela Ramírez Ortega, Veronica Pérez de la Cruz, Maria Eva González-Trujano, C López-Rubalcava

Open access · goldAbstract read
In one paragraph

Article in Frontiers in behavioral neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Ethanolic Extract of Pomegranate (Animals : an open access journal from MDPI · 2025
    Article
  3. Role of Nitric Oxide in the Antidepressant Effect of an Aqueous Extract ofInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Preventive and Therapeutic Effects ofInternational journal of molecular sciences · 2023
    Review
  10. Antidepressant-like effects of theFrontiers in pharmacology · 2023
    Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Nancy Cervantes-AnayaLaboratorio de Neuropsicofarmacología, Dirección de Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Secretaria de Salud (SSA), Mexico City, Mexico.
Gabriel Azpilcueta-MoralesLaboratorio de Neuropsicofarmacología, Dirección de Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Secretaria de Salud (SSA), Mexico City, Mexico.
Erika Estrada-CamarenaLaboratorio de Neuropsicofarmacología, Dirección de Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Secretaria de Salud (SSA), Mexico City, Mexico.
Daniela Ramírez OrtegaLaboratorio de Neurobioquímica y Conducta, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Secretaria de Salud (SSA), Mexico City, Mexico.
Veronica Pérez de la CruzLaboratorio de Neurobioquímica y Conducta, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Secretaria de Salud (SSA), Mexico City, Mexico.
Maria Eva González-TrujanoLaboratorio de Neurofarmacología de Productos Naturales, Dirección de Neurociencias, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Secretaria de Salud (SSA), Mexico City, Mexico.
C López-RubalcavaLaboratorio 16, Departamento de Farmacobiología, Centro de Investigación y Estudios Avanzados, Mexico City, Mexico.
Secretaria de Salud · MXInstituto Nacional de Neurología y Neurocirugía · MXCentro de Investigación en Materiales Avanzados · MXInstituto Nacional de Psiquiatría · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous reports described the antidepressant-like action of the aqueous extract of pomegranate (

Indexed as

antidepressant-like effectantioxidantaqueous extract of Punica granatum (AEPG)ellagic acidfree radical-scavenging activityovariectomypomegranatepunicalagin

Identifiers

PMID35600992
PMCPMC9120967
OpenAlexW4229043699

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.