Evidence map›Paper›PMID 35601102›Full record

ReviewFrontiers in cellular and infection microbiology2022

Tag Thy Neighbour: Nanometre-Scale Insights Into Kinetoplastid Parasites With Proximity Dependent Biotinylation.

Vincent Geoghegan, Jeremy C Mottram, Nathaniel G Jones

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Mapping Trypanosoma Protein Interactome by Proximity-Dependent Biotinylation.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Vincent GeogheganDepartment of Biology, York Biomedical Research Institute, University of York, York, United Kingdom.
Jeremy C MottramDepartment of Biology, York Biomedical Research Institute, University of York, York, United Kingdom.
Nathaniel G JonesDepartment of Biology, York Biomedical Research Institute, University of York, York, United Kingdom.
University of York · GB

Funding

Medical Research Council MR/P027989/1Wellcome TrustWellcome Trust 200807/Z/16/Z
6 · The paper itself

Abstract

Proximity labelling is a powerful and rapidly developing technology for exploring the interaction space and molecular environment of a protein of interest at the nanometre scale. In proximity labelling, a promiscuous biotinylating enzyme is genetically fused to the protein of interest, initiation of labelling then results in the biotinylating enzyme generating reactive biotin which covalently 'tags' nearby molecules. Importantly, this labelling takes place

Indexed as

KinetoplastidaParasitesAnimalsBiotinBiotinylationHumansBiotinAPEX2BioID proximity labelingbiotinylationBirA enzymekinetoplastidleishmaniamass spectrometry - LC-MS/MSproteomicstrypanosoma

Identifiers

PMID35601102
PMCPMC9120650
OpenAlexW4229062818

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.