Evidence map›Paper›PMID 35601996›Full record

ArticleZoonoses (Shannon, Ireland)2022

Current understanding of extracellular vesicle homing/tropism.

Mariola J Edelmann, Peter E Kima

Open access · diamondAbstract read
In one paragraph

Article in Zoonoses (Shannon, Ireland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. The Reality of Active Targeting in Nanomedicine: Promise Versus Performance.Chembiochem : a European journal of chemical biology · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Extracellular vesicles decoying across host immunity.Journal of leukocyte biology · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 3 countries.

Mariola J EdelmannDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, United States of America.
Peter E KimaDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, United States of America.
Guangzhou Medical University · CN

Funding

Extracellular vesicle biogenesis and Leishmania lesion developmentR56AI143293 · NIAID · UNIVERSITY OF FLORIDA · PI KIMA, PETER E. · 2019 to 2019
$383k
Function and protein cargo of exosomes in antigen presenting cells during Salmonella infectionR03AI135610 · NIAID · UNIVERSITY OF FLORIDA · PI FERRARO, MARIOLA JADWIGA · 2019 to 2020
$140k
NIAID NIH HHS R03 AI135610NIAID NIH HHS R56 AI143293
6 · The paper itself

Abstract

Extracellular vesicles (EVs) are membrane-enclosed packets released from cells that can transfer bioactive molecules from cell to cell without direct contact with the target cells. This transfer of molecules can activate consequential processes in the recipient cells, including cell differentiation and migration that maintain tissue homeostasis or promote tissue pathology. One controversial aspect of the EV's biology that holds therapeutic promise is their capacity to engage defined cells at specific sites. On the one hand, persuasive studies have shown that EVs express surface molecules that ensure their tissue localization and enable cell-specific interactions, as demonstrated using

Indexed as

Extracellular vescileshomingintracellular infection

Identifiers

PMID35601996
PMCPMC9121623
OpenAlexW4280530868

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.